Results 81 to 90 of about 15,212,696 (301)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Bayesian Semiparametric Inference in Multiple Equation Models [PDF]

open access: yes
This paper outlines an approach to Bayesian semiparametric regression in multiple equation models which can be used to carry out inference in seemingly unrelated regressions or simultaneous equations models with nonparametric components.
Gary Koop, Dale Poirier, Justin Tobias
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

ANALISIS HUBUNGAN ANTARA KETERSEDIAAN PUSAT INFORMASI DAN INTENSITAS PUBLIKASI KEGIATAN WISATA TERHADAP KONTRIBUSI EKONOMI SEKTOR PARIWISATA

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2012
Penelitian ini ditujukan untuk menganalisis hubungan antara ketersediaan pusat informasi dan intensitas publikasi kegiatan wisata terhadap Kontribusi Ekonomi Sektor Pariwisata.
Wahyudi Sutopo
doaj   +1 more source

Models with Simultaneous Equations for Local Development [PDF]

open access: yesTheoretical and Applied Economics, 2010
This paper presents a model based on simultaneous equations with statistical determined parameters for describing the evolution of important issues relating to local development. The main issues considered are public and private business development environment, employment, demography, social comfort, etc.
Ani MATEI, Stoica ANGHELESCU
openaire   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Estimation of a Simultaneous Model of Married Women's Labor Force Participation and Fertility in Urban Japan [PDF]

open access: yes
A strong and negative correlation between married women's labor force participation and fertility has been witnessed in Japan in past decades. Relative to empirical studies of a traditional single equation on female labor supply, there exist few ...
Tetsuji Yamada, Tadashi Yamada
core  

Endogeneity in quantile regression models: a control function approach [PDF]

open access: yes, 2004
This paper considers a linear triangular simultaneous equations model with conditional quantile restrictions. The paper adjusts for endogeneity by adopting a control function approach and presents a simple two-step estimator that exploits the partially ...
Lee, S., Lee, Sokbae, Sokbae (Simon) Lee
core   +1 more source

How do volatile and non-volatile energy factors affect energy OFDI? evidence from simultaneous equation model

open access: yesFrontiers in Energy Research
Its reliance on energy from individual countries has seriously affected its energy security and foreign policy. Therefore, reducing dependence on energy from specific countries and decomposing energy import channels have become crucial goals in China’s ...
Yanfeng Liu   +6 more
doaj   +1 more source

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