Results 61 to 70 of about 118,243 (256)

POVERTY MACRO SYSTEM DYNAMICS MODELING BASED ON SIMULTANEOUS EQUATIONS MODELS

open access: yesBarekeng
Poverty factors are multidimensional and complex. Currently, to predict the number of people living below the poverty line using the concept of linear thinking.
Bagus Sumargo   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Adoption of Innovative Energy Facilities in the Tertiary Sector Buildings: Exploring Interdependencies and Key Drivers

open access: yesBuildings
Innovative energy facilities, such as solar panels, heat pumps, and smart control ventilation, offer substantial opportunities to improve energy efficiency and environmental performance in the tertiary sector, aligning with green building objectives ...
Ruijin Huang, Gaofeng Gu
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The interrelationships between economic growth and innovation: international evidence

open access: yesJournal of Applied Economics
Technological innovation towards the goal of sustainable development is one of the concerns of many countries. This research investigates the linkages between innovation and growth for 71 countries worldwide from 1996 to 2020 by employing a simultaneous ...
Duyen My Thi Thi, Tinh Tran Phu Do
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ANALISIS HUBUNGAN ANTARA KETERSEDIAAN PUSAT INFORMASI DAN INTENSITAS PUBLIKASI KEGIATAN WISATA TERHADAP KONTRIBUSI EKONOMI SEKTOR PARIWISATA

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2012
Penelitian ini ditujukan untuk menganalisis hubungan antara ketersediaan pusat informasi dan intensitas publikasi kegiatan wisata terhadap Kontribusi Ekonomi Sektor Pariwisata.
Wahyudi Sutopo
doaj   +1 more source

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