Results 71 to 80 of about 125,136 (305)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Adoption of Innovative Energy Facilities in the Tertiary Sector Buildings: Exploring Interdependencies and Key Drivers

open access: yesBuildings
Innovative energy facilities, such as solar panels, heat pumps, and smart control ventilation, offer substantial opportunities to improve energy efficiency and environmental performance in the tertiary sector, aligning with green building objectives ...
Ruijin Huang, Gaofeng Gu
doaj   +1 more source

Coherency Conditions In Simultaneous Linear Equation Models With Endogenous Switching Regimes [PDF]

open access: yes
In modeling disequilibrium macroeconomic systems which one would want to subject to econometric estimation one typically faces the problem of whether the structural model can determine a unique equilibrium. The problem inherits a special form because the
A. Monfort   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The interrelationships between economic growth and innovation: international evidence

open access: yesJournal of Applied Economics
Technological innovation towards the goal of sustainable development is one of the concerns of many countries. This research investigates the linkages between innovation and growth for 71 countries worldwide from 1996 to 2020 by employing a simultaneous ...
Duyen My Thi Thi, Tinh Tran Phu Do
doaj   +1 more source

Bayesian Semiparametric Inference in Multiple Equation Models [PDF]

open access: yes
This paper outlines an approach to Bayesian semiparametric regression in multiple equation models which can be used to carry out inference in seemingly unrelated regressions or simultaneous equations models with nonparametric components.
Gary Koop, Dale Poirier, Justin Tobias
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Models with Simultaneous Equations for Local Development [PDF]

open access: yesTheoretical and Applied Economics, 2010
This paper presents a model based on simultaneous equations with statistical determined parameters for describing the evolution of important issues relating to local development. The main issues considered are public and private business development environment, employment, demography, social comfort, etc.
Ani MATEI, Stoica ANGHELESCU
openaire   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

ANALISIS HUBUNGAN ANTARA KETERSEDIAAN PUSAT INFORMASI DAN INTENSITAS PUBLIKASI KEGIATAN WISATA TERHADAP KONTRIBUSI EKONOMI SEKTOR PARIWISATA

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2012
Penelitian ini ditujukan untuk menganalisis hubungan antara ketersediaan pusat informasi dan intensitas publikasi kegiatan wisata terhadap Kontribusi Ekonomi Sektor Pariwisata.
Wahyudi Sutopo
doaj   +1 more source

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