Results 71 to 80 of about 6,395,940 (332)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A nonlinear simultaneous equation model to determine taper curve.

open access: yesSilva Fennica, 1979
In the original set of equations derived by regression analysis, relative-height diameters (endogenous variables) are presented as nonlinear functions of the other relative-height diameters and of the height of the tree (an exogenous variable).
Kilkki, Pekka, Varmola, Martti
doaj   +1 more source

Luminosity distance and redshift in the Szekeres inhomogeneous cosmological models

open access: yes, 2011
The Szekeres inhomogeneous models can be used to model the true lumpy universe that we observe. This family of exact solutions to Einstein's equations was originally derived with a general metric that has no symmetries. In this work, we develop and use a
Anthony Nwankwo   +17 more
core   +1 more source

Numerical Solution of Quantum-Mechanical Pair Equations [PDF]

open access: yes, 1968
We discuss and illustrate the numerical solution of the differential equation satisfied by the first‐order pair functions of Sinanoğlu. An expansion of the pair function in spherical harmonics and the use of finite difference methods convert the ...
McKoy, Vincent, Winter, N. W.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Models with Simultaneous Equations for Local Development [PDF]

open access: yesTheoretical and Applied Economics, 2010
This paper presents a model based on simultaneous equations with statistical determined parameters for describing the evolution of important issues relating to local development.
Ani MATEI, Stoica ANGHELESCU
doaj   +1 more source

Dynamic Interaction Between Microfinance and Household Well-Being: Evidence from the Microcredit Progressive Model for Sustainable Development

open access: yesEconometrics
Microfinance aims to promote financial inclusion among underprivileged individuals, particularly through progressive microcredit, which enables borrowers to access increasing loan amounts over time.
Ahmad Alqatan   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Conditions for the existence of control functions in nonseparable simultaneous equations models [PDF]

open access: yes
The control function approach (Heckman and Robb (1985)) in a system of linear simultaneous equations provides a convenient procedure to estimate one of the functions in the system using reduced form residuals from the other functions as additional ...
Richard Blundell, Rosa Matzkin
core  

Design of dissipative linear phase filters [PDF]

open access: yes, 1968
Set of design curves eliminates work involved in designing linear phase filters by being normalized in such a way as to apply to low, band, and high-pass filters of any bandwidth.
Phares, R. L.
core   +1 more source

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