Results 71 to 80 of about 99,043 (294)

Path Forecast Evaluation [PDF]

A path forecast refers to the sequence of forecasts 1 to H periods into the future. A summary of the range of possible paths the predicted variable may follow for a given confidence level requires construction of simultaneous confidence regions that ...
Oscar Jorda, Massimiliano Marcellino
core   +3 more sources

Evaluation of intravoxel incoherent motion fitting methods in low-perfused tissue [PDF]

, 2017
PURPOSE: To investigate the robustness of constrained and simultaneous intravoxel incoherent motion (IVIM) fitting methods and the estimated IVIM parameters (D, D* and f) for applications in brain and low-perfused tissues.MATERIALS AND METHODS: Model ...
Novak, Jan, Peet, A.C., Emma M. Meeus, Dehghani, Hamid; id_orcid, Zarinabad, N., Hamid Dehghani, Novak, J., Withey, Stephanie B., Stephanie B. Withey, Zarinabad, Niloufar, Jan Novak, Niloufar Zarinabad, Andrew C. Peet, Peet, Andrew, Meeus, E.M., Meeus, Emma M, Withey, S.B., Dehghani, H.   +17 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Object segmentation by fitting statistical shape models : a Kernel-based approach with application to wisdom tooth segmentation from CBCT images [PDF]

, 2014
Image segmentation is an important and challenging task in medical image analysis. Especially from low-quality images, segmentation algorithms have to cope with misleading background clutter, insufficient object boundaries and noise in the image ...
Jud, Christoph
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A comparison of SuperDARN ACF fitting methods [PDF]

, 2013
The Super Dual Auroral Radar Network (SuperDARN) is a worldwide chain of HF radars which monitor plasma dynamics in the ionosphere. Autocorrelation functions are routinely calculated from the radar returns and applied to estimate Doppler velocity ...
Ribeiro, A. J., Baker, Joseph B. H., J. B. H. Baker, J. M. Ruohoniemi, K. Oksavik, R. A. Greenwald, A. J. Ribeiro, P. V. Ponomarenko, Ponomarenko, Pavlo V., de Larquier, S., Oksavik, Kjellmar, Greenwald, R. A., Clausen, Lasse B. N., S. de Larquier, L. B. N. Clausen, Ruohoniemi, J. Michael   +15 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Properties of Martian Hematite at Meridiani Planum by Simultaneous Fitting of Mars Mossbauer Spectra [PDF]

, 2010
Mossbauer spectrometers [1] on the two Mars Exploration Rovers (MERs) have been making measurements of surface rocks and soils since January 2004, recording spectra in 10-K-wide temperature bins ranging from 180 K to 290 K.
Agresti, D. G., Klingelhoefer, G., Morris, R. V., Fleischer, I.   +3 more
core   +1 more source