Results 91 to 100 of about 95,614 (254)

Determination of the conductivity and thickness of conductive layers on conductive base materials

Advances in Mechanical Engineering, 2019
An eddy current technique for the simultaneous determination of the layer thickness and conductivity of a uniform conductive layer on a known conductive base material is presented.
John Burkhardt
doaj   +1 more source

Twin-Core Fiber-Based Mach Zehnder Interferometer for Simultaneous Measurement of Strain and Temperature

Sensors, 2018
In this paper we present an all-fiber interferometric sensor for the simultaneous measurement of strain and temperature. It is composed of a specially fabricated twin-core fiber spliced between two pieces of a single-mode fiber.
Dominik Kowal, Waclaw Urbanczyk, Pawel Mergo   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Measurement of Planetary Boundary Layer Winds with Scanning Doppler Lidar

Remote Sensing, 2018
The accurate measurement of wind profiles in the planetary boundary layer (PBL) is important not only for numerical weather prediction, but also for air quality modeling.
Soojin Park, Sang-Woo Kim, Moon-Soo Park, Chang-Keun Song   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T.

PLoS ONE, 2019
γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter, is challenging to measure using proton spectroscopy due to its relatively low concentration, J-coupling and overlapping signals from other metabolites.
Donghyun Hong, Seyedmorteza Rohani Rankouhi, Jan-Willem Thielen, Jack J A van Asten, David G Norris   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Simultaneous Multi-Component Gas Detection Using Distributed Cavity-Enhanced Raman Spectroscopy with Band-Area Normalized Calibration

Applied Sciences
A distributed cavity-enhanced Raman spectroscopy system was developed for the simultaneous detection of H2, O2, N2, and CO2 in confined spaces and complex gas environments. The system adopts an external-host/distributed-detection-cavity configuration, in
Yu Li, Laiyong Song, Chunguang Li, Chen Chen, Jianyu Huang, Ce Yang, Mingming Wen   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Improving the SCS-CN method based on adjusting the main parameters using rainfall-runoff data

Journal of Hydrology: Regional Studies
Study region: The Paskouhak representative basin in southwestern Iran, lies in elevations ranging from 2007 to 2931 m, and a semi-arid climate, the basin drains into Maharlou Lake.
Peyman Afrasiabikia, Atefeh Parvaresh Rizi, Luca Brocca   +2 more
doaj   +1 more source