Results 111 to 120 of about 12,036 (231)

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

A Bayesian approach to spectroscopic depth sectioning for locating dopant atoms

Journal of Microscopy, EarlyView.
Abstract Locating dopants in 3D is of great interest as advanced materials and devices increasingly rely on control at atomic dimensions, and microscopy tools are constantly in development for this purpose. One potential tool is electron energy loss spectroscopy (EELS) depth sectioning, where a core‐loss signal is collected as a function of electron ...
Michael Deimetry, Timothy C. Petersen, Matthew Weyland, Scott D. Findlay   +3 more
wiley   +1 more source

Robust CDF‐Filtering of a Location Parameter

Journal of Time Series Analysis, EarlyView.
ABSTRACT This paper introduces a novel framework for designing robust filters associated with signal plus noise models having symmetric observation density. The filters are obtained by a recursion where the innovation term is a transform of the cumulative distribution function of the residuals.
Leopoldo Catania, Andrew C. Harvey, Alessandra Luati   +2 more
wiley   +1 more source

Perceptual Priors Update Contextual Feedback Processing in V1

Topics in Cognitive Science, EarlyView.
Abstract Contextual information and prior knowledge facilitate perceptual processing, improving our recognition of even distorted or obstructed visual inputs. As a result, neuronal processing elicited by identical sensory inputs varies depending on the context in which we encounter those inputs.
Yulia Y. Lazarova, Yingying Huang, Lars F. Muckli, Lucy S. Petro   +3 more
wiley   +1 more source

Distinctive neurophysiological correlates of sound onset and offset perception in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Electroencephalography (EEG) recordings were obtained from participants listening to successive pairs of 1‐2 s noises in a silent background (Study 1) or successive pairs 1‐2 s silent gaps in a noise background (Study 2). Participants heard the same stimuli in the context of either a duration discrimination task (identifying ...
Fatima Ali, Gabriela Bury, Adèle Simon, Jennifer F. Linden   +3 more
wiley   +1 more source

A Modified Balanced Steady State Free Precession Sequence for Overhauser Magnetic Resonance Imaging

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1655-1665, October 2026.
ABSTRACT Purpose Low‐ and ultralow‐field magnetic resonance imaging (ULF MRI) have inherently low signal‐to‐noise ratio (SNR) by design. Overhauser dynamic nuclear polarization (ODNP) stands out as an effective solution for continuous signal enhancement.
Kai Buckenmaier, Friedemann Bullinger, Georgiy Alekseevich Solomakha, Marcel Schneider, Jörn Engelmann, Philipp Pohlmann, Pavel Povolni, Laura Kuebler, André Ferreira Martins, Klaus Scheffler   +9 more
wiley   +1 more source

Concomitant Gradient Effects Across Field Strengths and Gradient Amplitudes: Improved Estimation of Errors and Correction of Concomitant Dephasing and Diffusion Weighting

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1178-1191, September 2026.
ABSTRACT Purpose Deleterious effects from concomitant gradients are amplified at lower field strengths and stronger gradients. We aimed to show the signal errors caused by concomitant gradients across a wide range of hardware configurations and propose corrections that can be applied during experimental design and analysis.
Viktor Olsson, Felix Mortensen, Emil Ljungberg, Frederik Testud, Ronnie Wirestam, Malwina Molendowska, Filip Szczepankiewicz   +6 more
wiley   +1 more source

Transverse Relaxation Time Constant of Cystathionine in Human Glioma at 3 T

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1076-1082, September 2026.
ABSTRACT Purpose Cystathionine (Cth) has emerged as a promising biomarker for identifying 1p/19q codeleted gliomas. However, little is known about the T2 relaxation time constant of Cth in gliomas. The aim of this study was to measure the T2 of Cth in vivo in glioma and compare it to the T2s of other metabolites at 3 T.
Dinesh K. Deelchand, Francesca Branzoli, Jamie D. Walls, Lucia Nichelli, Marc Sanson, Bertrand Mathon, Małgorzata Marjańska   +6 more
wiley   +1 more source

Multi-Omics Analysis Identifies Phosphoglucomutase 2 as a Potential Target to Alleviate Chemoradiotherapy Resistance in Cervical Cancer Cells. [PDF]

Onco Targets Ther
Yang H, Zheng Q, Li X, Wang J.
europepmc   +1 more source