Results 61 to 70 of about 12,685 (261)

A collocation method for solving boundary value problems of fractional order

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
In this paper, the sinc collocation method is used to obtain the solution of the second-order fractional boundary value problems based on the conformable fractional derivative. For this purpose a theorem is proved to represent the terms having fractional
Sertan Alkan, Aydin Seçer
doaj   +1 more source

How to generate accurate continuous thermal regimes from sparse but regular temperature measurements

Methods in Ecology and Evolution, 2023
In ecology, there is an emerging emphasis on the importance of capturing temperature variation at relevant scales. Temperature fluctuates continuously in nature but is sampled at discrete time points, so how often should ecologists measure temperature to
Loke vonSchmalensee
doaj   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Acoustic Green's Functions using the 2D Sinc-Galerkin Method [PDF]

, 2014
In many acoustic problems, the radiated sound field is dominated by scattering effects. Green's functions represent the scattering behaviour of a particular geometry and are required to propagate acoustic disturbances through complex geometries using ...
Dupère, Iain D. J., Harwood, Adrian R.G.; id_orcid   +1 more
core   +1 more source

A Novel sinc Interpolation for Continuous PRF Sampled Sequences Reconstruction in Spotlight SAR

Leida xuebao, 2019
This paper focuses on an improved imaging-algorithm for the spotlight Synthetic Aperture Radar (spotlight SAR) with continuous Pulse Repetition Frequency (PRF) variation in extremely high-resolution imaging-process.
CHEN Shiyang, HUANG Lijia, YU Lei
doaj   +1 more source

Convergence of approximate solution of delay Volterra integral equations [PDF]

Iranian Journal of Numerical Analysis and Optimization, 2016
In this paper, sinc-collocation method is discussed to solve Volterra func tional integral equations with delay function (t). Also the existence and uniqueness of numerical solutions for these equations are provided.
M. Zarebnia, Leila Shiri
doaj   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source