Results 171 to 180 of about 1,047,175 (209)

Sindbis Virus: A Newly Recognized Arthropod-Transmitted Virus

The American Journal of Tropical Medicine and Hygiene, 1955
Summary 1.  Studies on Sindbis virus, a newly recognized member of the arthropod-transmitted viruses, are described; these include data on its immunological characteristics, distribution in the Nile Valley, vertebrate host range, and transmissibility by arthropods. 2.
R M, TAYLOR, H S, HURLBUT, T H, WORK, J R, KINGSTON, T E, FROTHINGHAM   +4 more
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Lipid and protein organization in Sindbis virus

Journal of Molecular Biology, 1971
Abstract The radial electron density distribution in the Sindbis virus particle has been determined to a resolution of 28 A from measurements of spherically averaged X-ray diffraction. The most striking feature of the density profile is a deep minimum at r = 232A, from which we infer that the lipids of Sindbis virus are organized in a bilayer at ...
S C, Harrison, A, David, J, Jumblatt, J E, Darnell   +3 more
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Glycopeptides of the membrane glycoprotein of Sindbis virus

Journal of Molecular Biology, 1970
The membrane of the Sindbis virus (an arbovirus) is structurally simple; it is composed of lipids and a single glycoprotein of molecular weight estimated at 53,000 daltons. Digestion of the membrane glycoprotein with pronase yields a set of glycopeptides (largely polysaccharide) that can be characterized by molecular sieving. From virus grown in chick
Burge, Boyce W., Strauss, James H., Jr.
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Glycosylation of intracellular Sindbis virus glycoproteins

Biochemistry, 1982
Oligosaccharides of purified intracellular Sindbis virus glycoproteins have been examined by high-resolution Bio-Gel chromatography. The array of glycopeptides from cellular E1 and E2 appeared similar to the glycopeptides (S1, S2, S3, and S4) found in mature virus glycoproteins described previously [Hakimi, J., & Atkinson, P. H. (1980) Biochemistry 19,
J, Hakimi, P H, Atkinson
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Antibody-mediated activation of sindbis virus

Virology, 1988
The biological activity of an anti-Sindbis monoclonal antibody (MCAB 49) has been explored. The antibody recognizes an epitope on the E2 glycoprotein of Sindbis virus and, in the presence of complement (C'), neutralizes virus infectivity. In the absence of C', reaction of the antibody with our laboratory strain of Sindbis, SB, increased the number of ...
D C, Flynn, R A, Olmsted, J M, Mackenzie, R E, Johnston   +3 more
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Asymmetry of the lipid-bilayer of Sindbis virus

Chemistry and Physics of Lipids, 1976
The organization of the lipid bilayer of the enveloped Sindbis virus has been studied. In the model membrane which consists only of two virus specific glycoproteins and host derived lipids the latter were radioactively labelled with 14C-palmitic acid by prelabelling their BHK 21 host cell lipids.
W, Stoffel, W, Sorgo
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Crystallization of Sindbis virus and its nucleocapsid

Journal of Molecular Biology, 1992
Crystals of Sindbis virus, which contains a lipid-bilayer membrane, have been grown using polyethylene glycol. The space group is R32, a = b = 640 A, c = 1520 A. The crystals are highly mosaic, and recorded diffraction is therefore restricted to spacings of about 30 A.
S C, Harrison, R K, Strong, S, Schlesinger, M J, Schlesinger   +3 more
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Peptide composition of Sindbis virus variants

Archiv f�r die gesamte Virusforschung, 1970
The peptide composition of variants of Sindbis virus which differ in plaque-type, elution pattern from calcium phosphate columns and virulence in mice was analyzed. Differences in peptide number or composition were not detected in these variants. Since the Sindbis virion has an outer lipoprotein envelope which is derived at least in part from the ...
H R, Bose, M A, Brundige, G Z, Carl, B P, Sagik   +3 more
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Immunochemical studies of Sindbis virus variants

Archiv f�r die gesamte Virusforschung, 1973
We have demonstrated that the small plaque (SP) variant of Sindbis virus is more extensively neutralized by complete antibody and serum IgG fractions than is the large plaque (LP) variant. The Fc portion failed to demonstrate any neutralizing potential and did not block subsequent neutralization by IgG or Fab fragments.
C E, Pedersen, C R, Barrera, B P, Sagik
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Location of the Glycoprotein in the Membrane of Sindbis Virus

Nature New Biology, 1971
SINDBIS virus, which is transmitted by arthropods, consists of a nucleoprotein core within a lipid-containing envelope. Its components assemble at a cellular membrane and virus particles form by an outfolding of this membrane. Thus, such viruses provide useful systems for studies of the structure and synthesis of membranes.
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