Results 31 to 40 of about 3,861,359 (307)

Variations in Cell Surfaces of Estrogen Treated Breast Cancer Cells Detected by A Combined Instrument for Far-Field and Near-Field Microscopy

Analytical Cellular Pathology, 2002
The response of single breast cancer cells (cell line T‐47D) to 17β‐estradiol (E2) under different concentrations was studied by using an instrument that allows to combine far‐field light microscopy with high resolution scanning near‐field (AFM/SNOM ...
P. Perner, A. Rapp, C. Dressler, L. Wollweber, J. Beuthan, K. O. Greulich, M. Hausmann   +6 more
doaj   +1 more source

Single Cell Neurometabolomics [PDF]

ACS Chemical Neuroscience, 2017
Metabolomics, the characterization of metabolites and their changes within biological systems, has seen great technological and methodological progress over the past decade. Most metabolomic experiments involve the characterization of the small-molecule content of fluids or tissue homogenates.
Meng Qi, Marina C. Philip, Ning Yang, Jonathan V. Sweedler   +3 more
openaire   +2 more sources

Protocol to generate fast-dissociating recombinant antibody fragments for multiplexed super-resolution microscopy

STAR Protocols, 2023
Summary: Multiplexed high-density label super-resolution microscopy image reconstruction by integrating exchangeable single-molecule localization (IRIS) enables elucidating fine structures and molecular distribution in cells and tissues.
Qianli Zhang, Akitoshi Miyamoto, Naoki Watanabe   +2 more
doaj   +1 more source

Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging

mBio, 2021
A significant portion of world population still fails to brush teeth daily. As a result, the majority of the global adult population is afflicted with chronic gingivitis, and if it is left untreated, some of them will eventually suffer from periodontitis.
Shi Huang, Tao He, Feng Yue, Xiujun Xu, Lijiang Wang, Pengfei Zhu, Fei Teng, Zheng Sun, Xiaohui Liu, Gongchao Jing, Xiaoquan Su, Lijian Jin, Jiquan Liu, Jian Xu   +13 more
doaj   +1 more source

Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity

Journal for ImmunoTherapy of Cancer, 2023
Background Antineoplastic chemotherapies are dramatically efficient when they provoke immunogenic cell death (ICD), thus inducing an antitumor immune response and even tumor elimination.
Hui Wang, Mayu Sun, Xiaoguang Li, Jingquan Li, Jingyang Li, Huiyi Chen, Xiaoyu Han, Weida Li, Guanghuan Yang, Bao Guo   +9 more
doaj   +1 more source

High-throughput chromatin accessibility profiling at single-cell resolution. [PDF]

, 2018
Here we develop a high-throughput single-cell ATAC-seq (assay for transposition of accessible chromatin) method to measure physical access to DNA in whole cells.
Bostick, Magnolia, Brower, Kara, Farmer, Andrew, Fordyce, Polly, Greenleaf, William, Klemm, Sandy, Linnarsson, Sten, Mann, Ishminder, Mezger, Anja, Mir, Alain   +9 more
core   +3 more sources

Artificial intelligence‐assisted automatic and index‐based microbial single‐cell sorting system for One‐Cell‐One‐Tube

mLife, 2022
Identification, sorting, and sequencing of individual cells directly from in situ samples have great potential for in‐depth analysis of the structure and function of microbiomes.
Zhidian Diao, Lingyan Kan, Yilong Zhao, Huaibo Yang, Jingyun Song, Chen Wang, Yang Liu, Fengli Zhang, Teng Xu, Rongze Chen, Yuetong Ji, Xixian Wang, Xiaoyan Jing, Jian Xu, Yuandong Li, Bo Ma   +15 more
doaj   +1 more source

Collective and single cell behavior in epithelial contact inhibition [PDF]

, 2011
Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still poorly understood.
A. Puliafito, A. Sigal, Abercrombie, Abercrombie, B. I. Shraiman, Castor, Chaffer, Chen, D. K. Fygenson, Farhadifar, Fournier, Gaush, Guarino, Halbleib, Heckman, Huang, Jamora, Janmey, L. Hufnagel, Lecuit, Leevers, Mark, Martz, Matsubayashi, Minami, Nelson, Orsulic, P. Neveu, Pan, Petitjean, Pugacheva, Rauzi, Rothen-Rutishauser, S. Streichan, Sakisaka, Schwartz, Takai, Tokumaru, Yamada, Yeung, Yu, Zeng, Zhao   +42 more
core   +4 more sources

Mitochondrial oxidative phosphorylation (mtOXPHOS) serves as a sentinel to gauge fluctuations under heat stress in Arabidopsis thaliana elucidated by comparative transcriptomics

Plant Stress
Heat stress has destructive effects on crop production and quality posing a grave threat to food security worldwide. Recent studies have elucidated the complicated transcriptional regulatory networks involved in heat stress, but how the organelles of ...
Muhammad Riaz, Erum Yasmeen, Moyang Liu, Hafiz Saqib Ali, Mengli Lv, Hu Shi, Chuanhui Du, Tiantian Dong, Zhenxin Liu, Qingwei Song, QiJun Ma, Kaijing Zuo   +11 more
doaj   +1 more source

Single-cell atomic quantum memory for light

, 2005
Recent experiments demonstrating atomic quantum memory for light [B. Julsgaard et al., Nature 432, 482 (2004)] involve two macroscopic samples of atoms, each with opposite spin polarization.
Opatrny, Tomas
core   +1 more source