Results 171 to 180 of about 5,714,705 (321)

Single-Cell Analysis Identifies Distinct Populations of Cytotoxic CD4+ T Cells Linked to the Therapeutic Efficacy of Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma

Journal of Inflammation Research
Xu Yang,1,* Jianwei Wu,1,* Longlong Fan,2 Binghua Chen,3 Shiqiang Zhang,4 Wenzhong Zheng1 1Department of Urology, Fujian Medical University Union Hospital, Fuzhou, People’s Republic of China; 2Department of Urology, The Eighth Affiliated Hospital,
Yang X, Wu J, Fan L, Chen B, Zhang S, Zheng W   +5 more
doaj  

Single-cell multi-omics analysis decodes molecular characteristics of sheep oocyte fate in vivo maturation

Yujun Yao, Zihuan Du, Qiang Zhang, Xiaochen Kou, Hongyu Yang, Chanyuan Pan, Jing Li, Xiangwei Sun, Lu Zhang, Guoshi Liu, Xiaoling Xu, Shuai Gao   +11 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Integrated Single-Cell and Transcriptome Analysis with Experimental Validation Reveals PANoptosis-Related Gene Signatures in the Immune Microenvironment of Autoimmune Thyroiditis

Journal of Inflammation Research
Zhuo Zhao,1,* Ziyu Liu,2,* Qun Wang,3,4 Hao Gao,1 Nan Song,5 Xiao Yang1,2 1The Second Clinical College of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning Province, People’s Republic of China; 2The Second Affiliated
Zhao Z, Liu Z, Wang Q, Gao H, Song N, Yang X   +5 more
doaj  

Editorial: Single cell analysis of bacteria-host interaction

Frontiers in Cellular and Infection Microbiology, 2023
Ondrej Cerny, Camilla Godlee, Damián Lobato-Márquez   +2 more
doaj   +1 more source

Single-cell analysis and control of microbial systems using optogenetics. [PDF]

Curr Opin Microbiol
Huang H, Dunlop MJ.
europepmc   +1 more source

Table 6_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv

Xiaofeng Li (342614), Weimin Wu (505435), Jie Tao (227070), Xiaoqing Guo (551753)   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Protocol for retinal stress culture and single-cell analysis. [PDF]

STAR Protoc
Norrie JL, Ramirez C, Dyer MA.
europepmc   +1 more source

Geometric Constraints and Vulnerability in Single-Cell ATAC-seq Immune States: Analysis Pipeline and Data

Elkin Alejandro Blanco Navarro
openalex   +1 more source