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Single-cell immune repertoire analysis
Nature MethodsSingle-cell T cell and B cell antigen receptor-sequencing data analysis can potentially perform in-depth assessments of adaptive immune cells that inform on understanding immune cell development to tracking clonal expansion in disease and therapy. However, it has been extremely challenging to analyze and interpret T cells and B cells and their adaptive
Sergio E. Irac +3 more
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Single‐Cell Transcriptomic Analysis
Comprehensive Physiology, 2020AbstractSingle‐cell sequencing measures the sequence information from individual cells using optimized single‐cell isolation protocols and next‐generation sequencing technologies. Recent advancement in single‐cell sequencing has transformed biomedical research, providing insights into diverse biological processes such as mammalian development, immune ...
Zhihong Zheng +7 more
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Single Cell Analysis of Proteoforms
Journal of Proteome ResearchWe introduce single cell Proteoform imaging Mass Spectrometry (scPiMS), which realizes the benefit of direct solvent extraction and MS detection of intact proteins from single cells dropcast onto glass slides. Sampling and detection of whole proteoforms by individual ion mass spectrometry enable a scalable approach to single cell proteomics.
Pei Su +12 more
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Single-Cell Transcriptomic Analysis.
Comprehensive Physiology, 2021Single-cell sequencing measures the sequence information from individual cells using optimized single-cell isolation protocols and next-generation sequencing technologies. Recent advancement in single-cell sequencing has transformed biomedical research, providing insights into diverse biological processes such as mammalian development, immune system ...
Zhihong, Zheng +7 more
openaire +1 more source