Results 231 to 240 of about 5,699,590 (286)

Spatial single-cell analysis reveals tumor microenvironment signatures predictive of oral cavity cancer outcome. [PDF]

Cell Rep Med
Näsiaho J, Nissi L, Ventelä S, Irjala H, Salmi M.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Three-dimensional forward-scattering imaging flow cytometry system for single-cell analysis. [PDF]

APL Photonics
Zhou M, Zhao J, Chen X, Zhang Z, Lai Z, Zhou Z, de la Zerda A, Lo YH.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Integrative Multi-Omics and Single-Cell Analysis Reveal THOC3 and THOC7 as Oncogenic RNA Processing Regulators in Lung Adenocarcinoma. [PDF]

Int J Med Sci
Kumar S, Wu CC, Solomon DD, Yen MC, Yeh IJ, Ko CC, Xuan DTM, Chang KF, Lin HR, Lin HY, Shih CL, Chen JB, Lee WY, Wang CY, Lee YK, Nguyen NUN.   +15 more
europepmc   +1 more source

Identification of immune-relevant candidate genes in atherosclerosis by WGCNA and single-cell analysis. [PDF]

Medicine (Baltimore)
Cao Y, Wei Y, Xue R, Yang Y, Sun W, Dong W.   +5 more
europepmc   +1 more source

Integrative Single-Cell Analysis Reveals Targetable Vacuole Membrane Protein 1-Mediated Mechanism of Tumor Angiogenesis in Glioblastoma. [PDF]

MedComm (2020)
Jin L, Chen B, Liao J, Guo W, Zhu Z, Ali S, Leung GK, Wang P, Kiang KM.   +8 more
europepmc   +1 more source

Identification of papillary thyroid carcinoma-associated epithelial cell subpopulations and diagnostic biomarkers: integrating machine learning with single-cell analysis. [PDF]

Transl Cancer Res
Zhai X, Gu X, Zhang S, Huang H, Ye H.
europepmc   +1 more source