Results 41 to 50 of about 731,457 (305)
Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates
Genome Biology, 2023 Background RNA velocity analysis of single cells offers the potential to predict temporal dynamics from gene expression. In many systems, RNA velocity has been observed to produce a vector field that qualitatively reflects known features of the system ...
Shijie C. Zheng +4 more
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Single cell RNA sequencing research in maternal fetal interface
Frontiers in Cell and Developmental Biology, 2023 The maternal-fetal interface is an essential environment for embryonic growth and development, and a successful pregnancy depends on the dynamic balance of the microenvironment at the maternal-fetal interface.
Qian Chen +16 more
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Revolutionizing immunology with single-cell RNA sequencing [PDF]
Cellular & Molecular Immunology, 2019 The immune system is composed of a complex hierarchy of cell types that protect the organism against disease and maintain homeostasis. Identifying heterogeneity of immune cells is the key to understanding the immune system. Advanced single-cell RNA sequencing (scRNA-seq) technologies are revolutionizing our ability to study immunology.
Haide, Chen, Fang, Ye, Guoji, Guo
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Development of methods for the analysis of deep sequencing data; applications to the discovery of functions of RNA-binding proteins [PDF]
, 2014 With the recent advances in nucleotide sequencing technologies, it became easy to generate tens of millions of reads with genome- or transcriptome-wide distribution with reduced cost and high accuracy.
Bilen, Biter
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The Technology and Biology of Single-Cell RNA Sequencing [PDF]
Molecular Cell, 2015 The differences between individual cells can have profound functional consequences, in both unicellular and multicellular organisms. Recently developed single-cell mRNA-sequencing methods enable unbiased, high-throughput, and high-resolution transcriptomic analysis of individual cells. This provides an additional dimension to transcriptomic information
Kolodziejczyk, Aleksandra A. +4 more
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Single-cell RNA sequencing of human kidney
, 2023 A comprehensive cellular anatomy of normal human kidney is crucial to address the cellular origins of renal disease and renal cancer. Some kidney diseases may be cell type-specific, especially renal tubular cells.
huan yang (17600760)
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Technology in Cancer Research & Treatment, 2022 Introduction: The application of single-cell RNA sequencing to delineate tissue heterogeneity and complexity has become increasingly popular. Given its tremendous resolution and high-dimensional capacity for in-depth investigation, single-cell RNA ...
GS Chuwdhury MPhil +2 more
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Computational and Structural Biotechnology Journal, 2023 Obesity affects the function of multiple organs/tissues including the exocrine organ salivary glands. However, the effects of obesity on transcriptomes and cell compositions in the salivary glands have yet been studied by bulk RNA-sequencing and single ...
Heping Huang +5 more
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Computational analysis of next generation sequencing data : from transcription start sites in bacteria to human non-coding RNAS [PDF]
, 2014 The advent of next generation sequencing (NGS) technologies has revolutionized the field of molecular biology by providing a wealth of sequence data. “Transcriptomics”, which aims to identify and annotate the complete set of RNA molecules transcribed ...
Jorjani, Hadi
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Nuclear RNA sequencing of the mouse erythroid cell transcriptome
, 2012 Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Umlauf David +39 more
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