Results 201 to 210 of about 763,272 (322)

Characterization of a Potential Therapeutic Anti-Canine PD-1 Single Domain Antibody Produced in Yeast. [PDF]

Vet Sci
Vijayasimha K, Annalora AJ, Mourich DV, Ruby CE, Dolan BP, Crowell L, Le VHM, Larson MK, Bracha S, Cebra CK.   +9 more
europepmc   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Editorial: Single-domain antibodies—biology, engineering and emerging applications, volume II

Frontiers in Immunology
Kevin A. Henry, Kevin A. Henry, Greg Hussack, Jan Gettemans, Cory L. Brooks   +4 more
doaj   +1 more source

In vitro and in vivo neutralization of Dengue virus by a single domain antibody. [PDF]

Immunohorizons
Dahiya S, Singh S, Bhati GK, Sehrawat S.
europepmc   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody. [PDF]

Elife
Pinto Torres JE, Claes M, Hendrickx R, Yuan M, Smiejkowska N, Van Wielendaele P, Hacisuleyman A, De Winter H, Muyldermans S, Michels PAM, Walkinshaw MD, Versées W, Caljon G, Magez S, Sterckx YG.   +14 more
europepmc   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling. [PDF]

Proc Natl Acad Sci U S A
Ota N, Davies CW, Kang J, Yan D, Scherl A, Wong A, Cook R, Tao X, Dunlap D, Klabunde S, Mantik P, Mohanan V, Lin W, McBride J, Sadekar S, Storek KM, Lupardus P, Ye Z, Ackerly Wallweber H, Kiefer JR, Xu M, Chan P, Nagapudi K, Yi T, Koerber JT.   +24 more
europepmc   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Single-domain antibody-based noninvasive in vivo imaging of α-synuclein or tau pathology. [PDF]

Sci Adv, 2023
Jiang Y, Lin Y, Krishnaswamy S, Pan R, Wu Q, Sandusky-Beltran LA, Liu M, Kuo MH, Kong XP, Congdon EE, Sigurdsson EM.   +10 more
europepmc   +1 more source