Results 21 to 30 of about 30,553 (220)

Intervention strategy for sustainable waste management systems in developing countries using community of practice [PDF]

Global Journal of Environmental Science and Management
Collaborative systems from various sectors, including public community, are encouraged to tackle the complexity of waste problems. However, identifying the most effective intervention strategies to promote sustainable participation in collaboration ...
Sunarti ., M. Nuryana, W. Wiryanto, Buyamin ., A. Aswin, C. Permatasari, J.H. Tjakraatmadja   +6 more
doaj   +1 more source

Organizational Learning Process in Single, Double and Triple Loop Companies in a Post-Crisis Situation in the Textile Sector in Tunisia

Journal of Entrepreneurship & Organization Management, 2017
It is an “exploratory” research that tries to determine the most adopted organizational learning processes in postcrisis Textile companies in Tunisia to guarantee their continuity and their survival. The research methodology is summarized by the following steps: • Exploratory qualitative study (non-formal because of the refusal to allow recorded ...
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design of Adaptive Distributed Secondary Control Using Double-Hidden-Layer Recurrent-Neural-Network-Inherited Total-Sliding-Mode Scheme for Islanded Micro-Grid

IEEE Access, 2022
This study proposes an adaptive double-hidden-layer recurrent-neural-network (DRNN)-based distributed secondary control (ADRNN-SC) scheme for the voltage restoration and the optimal active power sharing in an islanded micro-grid (MG).
Quan-Quan Zhang, Rong-Jong Wai
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Assessment of the Sustainability Performance of Eco-Engineering Measures in the Mediterranean Region

Land, 2022
Eco-engineering has a crucial role in defining and achieving the sustainability credentials of a civil engineering project. Better eco-engineering practices would help better in reducing the adverse impacts on the environment and society, but also on the
Slobodan B. Mickovski, Alejandro Gonzalez-Ollauri, Craig Thomson, Caroline Gallagher, Guillermo Tardio   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source