Results 31 to 40 of about 30,553 (220)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Evaluation as Reflective Practice

Problemy Zarządzania, 2019
Reflective practice has become an influential concept in the evaluation field. A greater use of reflective practice is advocated in reference to both evaluators’ own professional development, and as a means to enhance dialogue, stakeholders ...
Paulina Kubera
doaj   +1 more source

Incident Causal Factors and the Reasons for Conducting Investigations: A Study of Five Ghanaian Large-Scale Mines

Safety, 2020
Background: This research sought to understand the perspective of mineworkers regarding incident investigations, with the objective of identifying incident investigations improvement opportunities.
Eric Stemn, Florence Ntsiful, Marconi Afenyo Azadah, Theophilus Joe-Asare   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A conceptual learning analysis of paired after action and intra action reviews for health emergencies

Learning Health Systems
Background Processes of self‐reflection and the learning they allow are crucial before, during, and after acute emergencies, including infectious disease outbreaks.
Elliot Brennan, Seye Abimbola
doaj   +1 more source

Engaged sustainability science and place-based transgressive learning in higher education

South African Journal of Science
This article is located within current debates on engaged science and learning in higher education, with emphasis on types of learning emerging from engaged sustainability science, and associated contributions to debates on decoloniality in higher ...
Heila Lotz-Sisitka, Lesley le Grange, Gibson Mphepo   +2 more
doaj   +1 more source

Green networks: Innovative capacity of SMEs in the Dutch greenhouse horticulture industry

Apstract: Applied Studies in Agribusiness and Commerce, 2012
The Dutch greenhouse horticulture industry is characterized by world leadership in high-tech innovation. The dynamics of this playing field are innovation in production systems and automation, reduction in energy consumption and sharing limited space ...
Henk J. Schout, Saskia J.M. Harkema
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Self-assessment as a heutagogical mechanism for double-loop learning in teacher induction

Frontiers in Education
IntroductionThe first year of teaching is often organized around external standards, leaving novice teachers limited authority over what counts as professional growth.
Ido Gideon
doaj   +1 more source