Results 171 to 180 of about 4,782 (272)

Prevalence of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease Patients With Frequent Exacerbations

Allergy, EarlyView.
Mireille C. Melles, Johannes C. C. M. in 't Veen, Dirk‐Jan Slebos, Frits M. E. Franssen, Marlies van Dijk, Pieter‐Paul W. Hekking   +5 more
wiley   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero, Brigida Boccanegra, Paola Mantuano, Antonietta Mele, Michela De Bellis, Roberta Lenti, Francesca Sanarica, Santa Cirmi, Elena Conte, Ornella Cappellari, Amber E. Sherrard, Ardawna Green, Mira Srinivasa, Marta L. Fiorotto, Annamaria De Luca   +14 more
wiley   +1 more source

Correction to: Single-Inhaler Triple Therapy and Health-Related Quality of Life in COPD: The IMPACT Study. [PDF]

Adv Ther, 2022
Tabberer M, Jones CE, Kilbride S, Halpin DMG, Lomas DA, Pascoe S, Singh D, Wise RA, Criner GJ, Lange P, Dransfield MT, Han MK, Martinez FJ, Kaisermann MC, Lipson DA.   +14 more
europepmc   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Economic evaluation of single-inhaler triple therapy for chronic obstructive pulmonary disease in Thailand. [PDF]

BMJ Open Respir Res
Dilokthornsakul P, Dilokthornsakul P, Chongmelaxme B, Niyompattama A.   +3 more
europepmc   +1 more source

Single-Inhaler Triple Therapy (SITT) for COPD: An Italian expert opinion paper on improving clinical outcomes and equity of therapeutic access. [PDF]

Multidiscip Respir Med
Bianco A, D'Antonio S, Lombardo FP, Micheletto C, Palcic S, Siscaro G, Pirina P.   +6 more
europepmc   +1 more source

Patient and Clinical Demographics of New Users to Single-Inhaler Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease. [PDF]

Pulm Ther, 2022
Wu B, Mannino D, Mu G, Stiegler M, Bogart M.   +4 more
europepmc   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

Cell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao, Yuqing Sun, Yutao Huang, Qinghang Meng, Xinhua Lin, Wei Wei, Xiaofang Tang   +6 more
wiley   +1 more source

Real-World Effectiveness and Safety of Single Inhaler Triple Therapy with Beclometasone/ Formoterol/ Glycopyrronium in Moderate to Severe Asthma: TriMaximize Study. [PDF]

J Asthma Allergy
Gessner C, Russell REK, Greulich T, Lommatzsch M, Suppli Ulrik C, Pohl W, Plaza V, Bourdin A, Kupczyk M, Braido F, Piraino A, Scaffidi-Argentina U, Bogoevska V, Trinkmann F, TriMaximize Core team, TriMaximize Core team, Akyildiz B, Fritz C, Grickschat V, Hahn A, Baumeister S, Richards J, Kisiel J, Krogh N.   +23 more
europepmc   +1 more source

Update on innovative surgical techniques for omphalectomy in foals

Equine Veterinary Education, EarlyView.
Summary Umbilical infection is a common foal disorder, prone to complications, requiring surgical excision in severe cases. Timely surgical excision is the treatment of choice in these cases, as the infected umbilicus places the foal at risk for further fatal complications, such as sepsis and septic arthritis.
O. Haion, A. J. Tatz, R. Dahan, G. Kelmer   +3 more
wiley   +1 more source