Results 211 to 220 of about 1,085,849 (268)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Objective clustering protocol for single-molecule data: A lifetime vs. intensity study. [PDF]

Biophys Rep (N Y)
Lovemore MAC, van Heerden B, Botha JL, Krüger TPJ.   +3 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging. [PDF]

Cell
Ma K, Ma X, Shida JF, Niu Z, Lin YK, Mandal S, Dobbins A, Golomb L, Eck MJ, Greulich H, Meyerson M, Peng CS.   +11 more
europepmc   +1 more source

Bridging single-molecule and genome-wide studies of cellular mRNA translation. [PDF]

RNA
Koch A, Tomuro K, Wakigawa T, Morisaki T, Iwasaki S, Stasevich TJ.   +5 more
europepmc   +1 more source

Characterizing the Impact of Nucleoid-Associated Proteins on HU-DNA Interactions by Live-Cell Single-Molecule Tracking. [PDF]

Chemphyschem
Fuller DEH, Dai X, McCarthy LA, Way LE, Wang X, Biteen JS.   +5 more
europepmc   +1 more source

Contrasting single-molecule magnet behaviour in dysprosium and terbium bis(stannolediide) complexes. [PDF]

Nat Chem
Sun X, Hinz A, Maier S, Gillhuber S, Jin D, Saito M, Weigend F, Schlittenhardt S, Moreno-Pineda E, Wernsdorfer W, Ruben M, Roesky PW.   +11 more
europepmc   +1 more source

Single-molecule readout of reversible nanoswitches enables continuous monitoring of low biomarker concentrations. [PDF]

Nat Commun
Vu C, Janssen SAJ, de Jong AM, Prins MWJ.   +3 more
europepmc   +1 more source

SMOLM-LFM: ratiometric single molecule orientation without polarizers

Vesga AG, Aleman-Castaneda L, Heil HS, Daly S, Bruggeman E, Lee SF, Brasselet S, Henriques R.   +7 more
europepmc   +1 more source

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SINGLE-MOLECULE SPECTROSCOPY

Annual Review of Physical Chemistry, 1997
▪ Abstract  Recent experimental and theoretical studies concerning single-molecule spectroscopy in solids are discussed. Pure quantum effects—such as photon bunching, antibunching, and spectral jumps—and more classical phenomena—such as near-field excitation, saturation, ac/dc Stark shifts, spectral diffusion, two-photon excitation, and customary ...
Plakhotnik, T, Donley, EA, Wild, UP
openaire   +6 more sources