Results 271 to 280 of about 730,667 (367)

Gastroesophageal reflux disease and risk of atrial fibrillation/flutter: Implications for heart failure progression

ESC Heart Failure, EarlyView.
Abstract Aims While observational studies suggest an association between gastroesophageal reflux disease (GERD) and atrial fibrillation/flutter (AF/AFL), the causal relationship and mechanisms remain undefined. This study employed Mendelian randomization (MR) to assess bidirectional causal relationships and explore potential implications for heart ...
Wansong Hu, Yingxing Wu, Wanqian Yu, Ping Li   +3 more
wiley   +1 more source

Clinical Impact of CTLA-4 Single-Nucleotide Polymorphism in DLBCL Patients Treated with CAR-T Cell Therapy. [PDF]

Curr Oncol
Seipel K, Shaforostova I, Nilius H, Bacher U, Pabst T.   +4 more
europepmc   +1 more source

Integrated trajectories of systolic and diastolic function differentially associate with risk for heart failure with preserved and reduced ejection fraction and proteomic profiles

European Journal of Heart Failure, EarlyView.
Graphical overview of derivation and testing of multiparametric trajectories of cardiac function. This study identified six trajectories of LV systolic and diastolic function from mid‐ to late‐life. Predicted trajectory from single echocardiogram identified four trajectories at differential risk for HFpEF and HFrEF.
Anne Marie Reimer Jensen, James C. Ross, Victoria Arthur, Michael E. Hall, Kunihiro Matsushita, Brandon Lennep, Pamela L. Lutsey, Tor Biering‐Sørensen, Amil M. Shah   +8 more
wiley   +1 more source

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

Journal of Immunology, 2012
Irini Evnouchidou, J. Birtley, S. Seregin, A. Papakyriakou, E. Zervoudi, M. Samiotaki, G. Panayotou, P. Giastas, Olivia Petrakis, D. Georgiadis, A. Amalfitano, E. Saridakis, I. Mavridis, E. Stratikos   +13 more
semanticscholar   +1 more source

Correction: Single Nucleotide Polymorphism Analysis of European Archaeological DNA.

PLoS ONE, 2010
Claire L. Watson, Elizabeth Popescu, Jesper Boldsen, Mario Slaus, Diana N. J. Lockwood   +4 more
doaj   +1 more source

Role of single-nucleotide polymorphism microarray in the classification of BAP1-inactivated melanocytic tumours. [PDF]

Histopathology
Durgin JS, Zoumberos NA, Novice T, Fullen DR, Hristov AC, Lowe L, Patel RM, Harms PW, Andea AA, Bresler SC.   +9 more
europepmc   +1 more source

Identification of single nucleotide polymorphisms (SNPs) in the transcriptome of sugarcane variety Co 86032 exposed to oxidative stress.

, 2019
S. Gayathri, M. Arockiyajainmary, R M Shalini, M. R. Vannish, A. Selvı, R. Manimekalai   +5 more
openalex   +1 more source

Deep phenotyping of heart failure with preserved ejection fraction through multi‐omics integration

European Journal of Heart Failure, EarlyView.
Deep phenotyping of of heart failure with preserved ejection fraction (HFpEF) through multi‐omics integration. AI, artificial intelligence. Aims Heart failure with preserved ejection fraction (HFpEF) has become the predominant form of heart failure and a leading cause of global cardiovascular morbidity and mortality.
Jakob Versnjak, Titus Kuehne, Pauline Fahjen, Nina Jovanovic, Ulrike Löber, Gabriele G. Schiattarella, Nicola Wilck, Holger Gerhardt, Dominik N. Müller, Frank Edelmann, Philipp Mertins, Roland Eils, Michael Gotthardt, Sofia K. Forslund, Benjamin Wild, Marcus Kelm   +15 more
wiley   +1 more source

Association Between Single-Nucleotide Polymorphism rs2287886 of <i>CD209</i> Gene and Clinical Severity of COVID-19 in Unvaccinated Brazilian Patients. [PDF]

Genes (Basel)
Galisa SLG, Silva RRCD, Aguiar MC, Sá MVBO, Melo JVO, Pereira GVN, Silva JRLE, Paiva BLX, Henrique AGDS, Carmo RFD, de Souza CDF, Armstrong ADC, Oliveira PRS, Silva Vasconcelos LR.   +13 more
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source