Results 21 to 30 of about 260,369 (317)
Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases. [PDF]
PLoS ONE, 2016 Systemic Autoimmune Diseases, a group of chronic inflammatory conditions, have variable symptoms and difficult diagnosis. In order to reclassify them based on genetic markers rather than clinical criteria, we performed clustering of Single Nucleotide ...
Thomas Charlon +8 more
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Picking single-nucleotide polymorphisms in forests [PDF]
BMC Proceedings, 2007 Abstract With the development of high-throughput single-nucleotide polymorphism (SNP) technologies, the vast number of SNPs in smaller samples poses a challenge to the application of classical statistical procedures. A possible solution is to use a two-stage approach for case-control data in which, in the first stage, a screening test selects
Silke Szymczak +3 more
openaire +3 more sources
Association of Single Nucleotide Polymorphisms in the PYGO2 and PRDM9 Genes with Idiopathic Azoospermia in Iranian Infertile Male Patients [PDF]
Iranian Journal of Medical Sciences, 2023 Background: Azoospermia is a risk factor for infertility affecting approximately 1% of the male population. Genetic factors are associated with non-obstructive azoospermia (NOA). Pygo2 and PRDM9 genes are involved in the spermatogenesis process.
Sanaz Soleymani Moud +3 more
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Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 63-70, January 2023., 2023 We found that microRNA‐196b‐5p was significantly upregulated in precancerous lesions and that combining it with other microRNAs increased the accuracy of detection. Since endoscopy is associated with risk, the identification of high‐risk groups for gastric cancer is expected to make it possible to clearly identify groups that should undergo endoscopy ...
Hajime Otsu +9 more
wiley +1 more source
Balkan Medical Journal, 2017 Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can +5 more
doaj +1 more source
Superoxide dismutase coding of gene polymorphisms associated with susceptibility to Parkinson’s disease [PDF]
Journal of Integrative Neuroscience, 2019 Oxidative stress linked to the etiology of Parkinson’s disease, which is characterized by chronic and progressive neurodegeneration of dopamine neurons.
Chunlei Liu, Jinju Fang, Wenke Liu
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Frontiers in Cellular and Infection Microbiology, 2022 BackgroundTuberculosis (TB) and AIDS are the leading causes of infectious diseases death worldwide. Here, we investigated the relationship between from single nucleotide polymorphisms (SNPs) of the NLRP3, CARD8, AIM2, CASP-1, IFI16, and IL-1β ...
Nathalia Beatriz Ramos de Sá +12 more
doaj +1 more source
Single nucleotide polymorphisms and cancer susceptibility [PDF]
Oncotarget, 2017 A large number of genes associated with various cancer types contain single nucleotide polymorphisms (SNPs). SNPs are located in gene promoters, exons, introns as well as 5'- and 3'- untranslated regions (UTRs) and affect gene expression by different mechanisms.
Heng Zhou, Na Deng, Hua Fan, Yuan Yuan
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Haematologica, 2008 The BCR-ABL K247R change is based on a rare single nucleotide polymorphism occurring likewise in healthy controls and non-hematologic cell types. Despite its juxtaposition to the P-loop, functional analysis showed no alteration compared to non-mutated ...
Thomas Ernst +7 more
doaj +1 more source
Tumor Biology, 2017 Chronic inflammation increases the risk of development of various cancers, including colorectal cancer. Interleukin-6 has been described as a key regulator of colorectal cancer development and is important in the process of colorectal tumorigenesis ...
Mujeeb Zafar Banday +4 more
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