Results 11 to 20 of about 746,762 (326)

Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array

Plant Biotechnology Journal, 2014
High-density single nucleotide polymorphism (SNP) genotyping arrays are a powerful tool for studying genomic patterns of diversity, inferring ancestral relationships between individuals in populations and studying marker–trait associations in mapping ...
Shichen Wang, Debbie Wong, K. Forrest, A. Allen, S. Chao, B. Huang, M. Maccaferri, S. Salvi, S. Milner, L. Cattivelli, A. Mastrangelo, A. Whan, S. Stephen, G. Barker, Ralf Wieseke, J. Plieske, International Wheat Genome Sequencing Consortium, M. Lillemo, D. Mather, R. Appels, R. Dolferus, G. Brown-Guedira, A. Korol, Alina Akhunova, C. Feuillet, J. Salse, M. Morgante, C. Pozniak, M. Luo, J. Dvorak, M. Morell, J. Dubcovsky, M. Ganal, R. Tuberosa, C. Lawley, Ivan Mikoulitch, C. Cavanagh, K. Edwards, M. Hayden, E. Akhunov   +39 more
semanticscholar   +3 more sources

Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test.

American Journal of Obstetrics and Gynecology, 2015
OBJECTIVE We sought to determine the ability of single-nucleotide polymorphism-based noninvasive prenatal testing (NIPT) to identify triploid, unrecognized twin, and vanishing twin pregnancies.
K. Curnow, L. Wilkins-Haug, A. Ryan, E. Kırkızlar, M. Stosic, M. Hall, S. Sigurjonsson, Z. Demko, M. Rabinowitz, S. Gross   +9 more
semanticscholar   +3 more sources

Clinical experience and follow-up with large scale single-nucleotide polymorphism-based noninvasive prenatal aneuploidy testing.

American Journal of Obstetrics and Gynecology, 2014
OBJECTIVE We sought to report on laboratory and clinical experience following 6 months of clinical implementation of a single-nucleotide polymorphism-based noninvasive prenatal aneuploidy test in high- and low-risk women.
P. Dar, K. Curnow, S. Gross, M. Hall, M. Stosic, Z. Demko, B. Zimmermann, M. Hill, S. Sigurjonsson, A. Ryan, M. Banjevic, P. Kolacki, Susanne Koch, C. Strom, M. Rabinowitz, P. Benn   +15 more
semanticscholar   +3 more sources

Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

Circulation Research, 2014
Rationale: Congenital heart disease (CHD) is among the most common birth defects. Most cases are of unknown pathogenesis. Objective: To determine the contribution of de novo copy number variants (CNVs) in the pathogenesis of sporadic CHD.
J. Glessner, Alexander G. Bick, K. Ito, Jason G. Homsy, Laura Rodríguez-Murillo, M. Fromer, Erica Mazaika, B. Vardarajan, Michael J. Italia, Jeremy Leipzig, S. DePalma, R. Golhar, Stephan J Sanders, B. Yamrom, M. Ronemus, I. Iossifov, A. Willsey, M. State, J. Kaltman, P. White, Yufeng Shen, D. Warburton, M. Brueckner, C. Seidman, E. Goldmuntz, B. Gelb, R. Lifton, J. Seidman, H. Hakonarson, W. Chung   +29 more
semanticscholar   +3 more sources

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

Cell, 2004
G. Bond, Wenwei Hu, E. Bond, Harlan Robins, S. Lutzker, Nicoleta C. Arva, J. Bargonetti, F. Bartel, Helge Taubert, Peter Wuerl, Kenan Onel, L. Yip, Shih-Jen Hwang, Louise C. Strong, G. Lozano, Arnold J. Levine   +15 more
semanticscholar   +3 more sources

The Utility of Single Nucleotide Polymorphism (SNP) Data in Phylogenetics

Annual Review of Ecology, Evolution, and Systematics, 2017
A. Leaché, Jamie R. Oaks
semanticscholar   +3 more sources

Single Nucleotide Polymorphism Identification in Polyploids: A Review, Example, and Recommendations.

Molecular Plant, 2015
J. Clevenger, Carolina Chavarro, S. Pearl, P. Ozias‐Akins, S. Jackson   +4 more
semanticscholar   +3 more sources

Impact of the Polymorphism of the PACRG and CD80 Genes on the Development of the Different Stages of Tuberculosis Infection [PDF]

Iranian Journal of Medical Sciences, 2019
Background: Tuberculosis (TB) is one of the most significant health-care problems worldwide. The host’s genetics play an important role in the development of TB in humans.
Elena Yu. Bragina, Nadezhda P. Babushkina, Anna F. Garaeva, Alexey A. Rudko, Dmitry Yu. Tsitrikov, Densema E. Gomboeva, Maxim B. Freidin   +6 more
doaj   +1 more source

p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]

, 2016
BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G, Fan, LM, Ghazaly, MM, Howlin, B, Krönke, M, Li, J-M, Meijles, DN   +6 more
core   +1 more source

Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans [PDF]

, 2020
OBJECTIVE: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ...
Dalton, C.F., Fernando, D.J., Illangasekera, Y.A., Kumarasiri, P.V.R.   +3 more
core   +1 more source