Results 21 to 30 of about 746,762 (326)

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic [PDF]

open access: yes, 2006
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene.
Nouvel, Laurent-Xavier   +9 more
core   +2 more sources

Whole genome sequencing options for bacterial strain typing and epidemiologic analysis based on single nucleotide polymorphism versus gene-by-gene-based approaches.

open access: yesClinical Microbiology and Infection, 2018
BACKGROUND Whole genome sequence (WGS)-based strain typing finds increasing use in the epidemiologic analysis of bacterial pathogens in both public health as well as more localized infection control settings. AIMS This minireview describes methodologic
A. Schürch   +3 more
semanticscholar   +1 more source

Investigations into the molecular effects of single nucleotide polymorphism [PDF]

open access: yes, 2000
Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe
core   +1 more source

Software for tag single nucleotide polymorphism selection

open access: yesHuman Genomics, 2005
This paper reviews the theoretical basis for single nucleotide polymorphism (SNP) tagging and considers the use of current software made freely available for this task. A distinction between haplotype block-based and non-block-based approaches yields two
Stram Daniel O
doaj   +1 more source

Simultaneous profiling of transcriptome and DNA methylome from a single cell. [PDF]

open access: yes, 2016
BackgroundSingle-cell transcriptome and single-cell methylome technologies have become powerful tools to study RNA and DNA methylation profiles of single cells at a genome-wide scale. A major challenge has been to understand the direct correlation of DNA
An, Qin   +9 more
core   +3 more sources

Identifying the similarities and differences between single nucleotide polymorphism array (SNPa) analysis and karyotyping in acute myeloid leukemia and myelodysplastic syndromes

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2015
Objective: To standardize the single nucleotide polymorphism array (SNPa) method in acute myeloid leukemia/myelodysplastic syndromes, and to identify the similarities and differ- ences between the results of this method and karyotyping.
Thiago Rodrigo de Noronha   +2 more
doaj   +1 more source

Bulk segregant analysis using single nucleotide polymorphism microarrays. [PDF]

open access: yesPLoS ONE, 2011
Bulk segregant analysis (BSA) using microarrays, and extreme array mapping (XAM) have recently been used to rapidly identify genomic regions associated with phenotypes in multiple species.
Anthony Becker   +4 more
doaj   +1 more source

Heterogeneous lengths of copy number mutations in human coagulopathy revealed by genome-wide high-density SNP array

open access: yesHaematologica, 2012
Background The recent advent of genome-wide molecular platforms has facilitated our understanding of the human genome and disease, particularly copy number aberrations.
Hee-Jin Kim   +10 more
doaj   +1 more source

The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs)

open access: yesJournal of Immunological Research, 2022
Interleukins (ILs)—which are important members of cytokines—consist of a vast group of molecules, including a wide range of immune mediators that contribute to the immunological responses of many cells and tissues.
P. Behzadi   +10 more
semanticscholar   +1 more source

Single Nucleotide Polymorphism Markers Associated with Seed Quality Characteristics of Cultivated Lentil

open access: yesThe Plant Genome, 2018
Only a few genomic regions control seed shape in lentil. Single nucleotide polymorphism markers associated with seed dimensions were identified. Lentil seed size is not dependent on cotyledon color.
H. Khazaei   +4 more
semanticscholar   +1 more source

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