Results 71 to 80 of about 730,667 (367)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Oxytocin receptor single nucleotide polymorphism predicts atony-related postpartum hemorrhage

BMC Pregnancy and Childbirth, 2022
Background Postpartum hemorrhage remains a key contributor to overall maternal morbidity in the United States. Current clinical assessment methods used to predict postpartum hemorrhage are unable to prospectively identify about 40% of hemorrhage cases ...
Elise N. Erickson, Kathleen M. Krol, Allison M. Perkeybile, Jessica J. Connelly, Leslie Myatt   +4 more
doaj   +1 more source

Genome sequencing of a Hevea brasiliensis for single nucleotide polymorphism discovery [PDF]

, 2013
The rubber tree (Hevea spp.), is the primary plant used in natural rubber production. Historically, the breeding of rubber trees has been based on techniques involving statistics and quantitative genetic approaches to determine the best genotypes to be ...
Cardoso-Silva, Claudio Benicio, Conson, Andre R.O., Garcia, Antonio Augusto Franco, Le Guen, Vincent, Mantello, Camilia Campos, Silva, Carla Cristina, Souza, Anete Pereira, Souza, Livia Moura, Toledo-Silva, Guilherme   +8 more
core  

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Boehm, Olaf, Bornstein, Stefan R., Grotemeyer, Dirk, Hamann, Lutz, Koch, Alexander, Kurt, Muhammed, Schott, Matthias, Schumann, Ralf R., Schwenke, Carsten, Zacharowski, Kai   +9 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Single Nucleotide Polymorphism (SNP) และ DNA Polymorphisms

Journal of Associated Medical Sciences, 2015
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Songyot Anuchapreeda
doaj  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

PLA2R1 and HLA-DQA1 SNP in patients with primary membranous nephropathy.

PLoS ONE
BackgroundPrimary membranous nephropathy is a widely recognized autoimmune disease associated with podocyte antigens; the most important autoantigen is PLA2R1. PLA2R1 and HLA-DQA1 play important roles in the production of pathogenic antibodies.
Junyi Zhou, Zhijian Zhang, Kezhi Zhou, Leting Zhou, Jing Xue, Bin Liu, Xiran Zhang, Ting Cai, Biao Huang, Yi Zhang, Zhigang Hu, Liang Wang, Xiaobin Liu   +12 more
doaj   +1 more source

Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]

, 2018
Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S, Annibali, O, Avvisati, G, Cantonetti, M, Circhetta, E, Franceschini, L, Piccioni, L, Riva, E., Rizzo, E, Sarlo, C, Scagnolari, C, Statzu, M, Tirindelli, Mc, Tomarchio, V   +13 more
core   +1 more source

Association of the fibronectin type III domain–containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans [PDF]

, 2023
Ricardo A. S. Lima‐Filho, Andréa Lessa Benedet, Marco Antônio De Bastiani, Guilherme Povala, Danielle Cozachenco, Sérgio T. Ferreira, Fernanda G. De Felice, Pedro Rosa‐Neto, Eduardo R. Zimmer, Mychael V. Lourenco   +9 more
openalex   +1 more source