Results 121 to 130 of about 495,951 (309)

Rayleigh-scattering microscopy for tracking and sizing nanoparticles in focused aerosol beams

IUCrJ, 2018
Ultra-bright femtosecond X-ray pulses generated by X-ray free-electron lasers (XFELs) can be used to image high-resolution structures without the need for crystallization.
Max F. Hantke, Johan Bielecki, Olena Kulyk, Daniel Westphal, Daniel S. D. Larsson, Martin Svenda, Hemanth K. N. Reddy, Richard A. Kirian, Jakob Andreasson, Janos Hajdu, Filipe R. N. C. Maia   +10 more
doaj   +1 more source

Orbital Angular Momentum Waves: Generation, Detection and Emerging Applications

, 2019
Orbital angular momentum (OAM) has aroused a widespread interest in many fields, especially in telecommunications due to its potential for unleashing new capacity in the severely congested spectrum of commercial communication systems.
Chen, Rui, Li, Jiandong, Moretti, Marco, Wang, Xiaodong, Zhou, Hong   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Highly sensitive volumetric single-molecule imaging

Nanophotonics
Volumetric subcellular imaging has long been essential for studying structures and dynamics in cells and tissues. However, due to limited imaging speed and depth of field, it has been challenging to perform live-cell imaging and single-particle tracking.
Wang Le-Mei, Kim Jiah, Han Kyu Young
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Image collection strategies for single particle cryoEM [PDF]

Microscopy and Microanalysis, 2021
Farzad Jalali-Yazdi, Eric Gouaux
openaire   +1 more source

Enhancing electrospray ionization efficiency for particle transmission through an aerodynamic lens stack

Journal of Synchrotron Radiation
This work investigates the performance of the electrospray aerosol generator at the European X-ray Free Electron Laser (EuXFEL). This generator is, together with an aerodynamic lens stack that transports the particles into the X-ray interaction vacuum ...
Safi Rafie-Zinedine, Tej Varma Yenupuri, Lena Worbs, Filipe R. N. C. Maia, Michael Heymann, Joachim Schulz, Johan Bielecki   +6 more
doaj   +1 more source

Talbot Oscillations and Periodic Focusing in a One-Dimensional Condensate

, 1999
An exact theory for the density of a one-dimensional Bose-Einstein condensate with hard core particle interactions is developed in second quantization and applied to the scattering of the condensate by a spatially periodic impulse potential.
A. G. Rojo, A. Lenard, B. Dubetsky, C. C. Bradley, D. G. Fried, D. M. Giltner, D. W. Keith, E. M. Rasel, G. Timp, H. F. Talbot, J. J. McClelland, J. Javanainen, J. Javanainen, J. L. Cohen, K. B. Davis, K. G. Singh, K. Patorski, M. Edwards, M. Edwards, M. Girardeau, M. H. Anderson, M. Kozuma, M. Lewenstein, M. S. Chapman, M.-O. Mewes, P. E. Moskowitz, P. R. Berman, P. Zoller, R. Penrose, S. Cahn, T. Sleator, T. T. Chou, U. Janicke   +32 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Single-shot femtosecond x-ray diffraction from randomly oriented ellipsoidal nanoparticles

Physical Review Special Topics. Accelerators and Beams, 2010
Coherent diffractive imaging of single particles using the single-shot “diffract and destroy” approach with an x-ray free electron laser (FEL) was recently demonstrated.
M. J. Bogan, S. Boutet, A. Barty, W. H. Benner, M. Frank, L. Lomb, R. Shoeman, D. Starodub, M. M. Seibert, S. P. Hau-Riege, B. Woods, P. Decorwin-Martin, S. Bajt, J. Schulz, U. Rohner, B. Iwan, N. Timneanu, S. Marchesini, I. Schlichting, J. Hajdu, H. N. Chapman   +20 more
doaj   +1 more source