Results 1 to 10 of about 3,960 (193)

50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative [PDF]

Journal of Synchrotron Radiation
We provide a historical introduction spanning the past 50 years of synchrotron radiation protein crystallography. We then provide a resume of current trends.
John R. Helliwell, Colin Nave, D. Marian Szebenyi   +2 more
doaj   +2 more sources

Thinner than a knife's edge: 3D-printed liquid sheet jet technology for solution phase XFEL experiments [PDF]

IUCrJ, 2023
In this commentary, we explore the pioneering implementation of 3D-printed thin liquid sheet devices for advanced X-ray scattering and spectroscopy experiments at high-repetition rate XFELs.
Martin Trebbin
doaj   +2 more sources

High-quality ultra-fast total scattering and pair distribution function data using an X-ray free-electron laser [PDF]

IUCrJ
High-quality total scattering data, a key tool for understanding atomic-scale structure in disordered materials, require stable instrumentation and access to high momentum transfers. This is now routine at dedicated synchrotron instrumentation using high-
Adam F. Sapnik, Philip A. Chater, Dean S. Keeble, John S. O. Evans, Federica Bertolotti, Antonietta Guagliardi, Lise J. Støckler, Elodie A. Harbourne, Anders B. Borup, Rebecca S. Silberg, Adrien Descamps, Clemens Prescher, Benjamin D. Klee, Axel Phelipeau, Imran Ullah, Kárel G. Medina, Tobias A. Bird, Viktoria Kaznelson, William Lynn, Andrew L. Goodwin, Bo B. Iversen, Celine Crepisson, Emil S. Bozin, Kirsten M. Ø. Jensen, Emma E. McBride, Reinhard B. Neder, Ian Robinson, Justin S. Wark, Michał Andrzejewski, Ulrike Boesenberg, Erik Brambrink, Carolina Camarda, Valerio Cerantola, Sebastian Goede, Hauke Höppner, Oliver S. Humphries, Zuzana Konopkova, Naresh Kujala, Thomas Michelat, Motoaki Nakatsutsumi, Alexander Pelka, Thomas R. Preston, Lisa Randolph, Michael Roeper, Andreas Schmidt, Cornelius Strohm, Minxue Tang, Peter Talkovski, Ulf Zastrau, Karen Appel, David A. Keen   +50 more
doaj   +2 more sources

Coaxial helium electrospray for single-particle imaging at X-ray free electron lasers [PDF]

Journal of Synchrotron Radiation
Single-particle imaging at X-ray free-electron lasers relies on suitable sample injection of nanoscale macromolecules and particles into the gas phase at room temperature.
Safi Rafie-Zinedine, Joachim Schulz, Johan Bielecki, Michael Heymann   +3 more
doaj   +2 more sources

A fixed-target platform for serial femtosecond crystallography in a hydrated environment [PDF]

IUCrJ, 2020
For serial femtosecond crystallography at X-ray free-electron lasers, which entails collection of single-pulse diffraction patterns from a constantly refreshed supply of microcrystalline sample, delivery of the sample into the X-ray beam path while ...
M. L. Shelby, D. Gilbile, T. D. Grant, C. Seuring, B. W. Segelke, W. He, A. C. Evans, T. Pakendorf, P. Fischer, M. S. Hunter, A. Batyuk, M. Barthelmess, A. Meents, M. A. Coleman, T. L. Kuhl, M. Frank   +15 more
doaj   +3 more sources

Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX

IUCrJ, 2022
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato   +11 more
doaj   +1 more source

Artificial intelligence for online characterization of ultrashort X-ray free-electron laser pulses

Scientific Reports, 2022
X-ray free-electron lasers (XFELs) as the world’s brightest light sources provide ultrashort X-ray pulses with a duration typically in the order of femtoseconds.
Kristina Dingel, Thorsten Otto, Lutz Marder, Lars Funke, Arne Held, Sara Savio, Andreas Hans, Gregor Hartmann, David Meier, Jens Viefhaus, Bernhard Sick, Arno Ehresmann, Markus Ilchen, Wolfram Helml   +13 more
doaj   +1 more source

3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers

IUCrJ, 2023
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in ...
Patrick E. Konold, Tong You, Johan Bielecki, Joana Valerio, Marco Kloos, Daniel Westphal, Alfredo Bellisario, Tej Varma Yenupuri, August Wollter, Jayanath C. P. Koliyadu, Faisal H.M. Koua, Romain Letrun, Adam Round, Tokushi Sato, Petra Mészáros, Leonardo Monrroy, Jennifer Mutisya, Szabolcs Bódizs, Taru Larkiala, Amke Nimmrich, Roberto Alvarez, Patrick Adams, Richard Bean, Tomas Ekeberg, Richard A. Kirian, Andrew V. Martin, Sebastian Westenhoff, Filipe R. N. C. Maia   +27 more
doaj   +1 more source

Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers

Crystals, 2020
With time-resolved crystallography (TRX), it is possible to follow the reaction dynamics in biological macromolecules by investigating the structure of transient states along the reaction coordinate.
Suraj Pandey, Ishwor Poudyal, Tek Narsingh Malla   +2 more
doaj   +1 more source

The Gamification of XFEL Education Using XFEL Crystal Blaster

Crystals, 2022
Novel groundbreaking techniques, such as serial femtosecond crystallography (SFX), which utilizes X-ray free-electron lasers (XFELs), have led to impressive advances in the field of structural biology. However, educating the next generation of scientists on this complex, advanced, and continuously evolving field can be challenging.
Fiacre Kabayiza, Sarah B. Woodruff, William J. Bauer   +2 more
openaire   +2 more sources