50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative [PDF]
We provide a historical introduction spanning the past 50 years of synchrotron radiation protein crystallography. We then provide a resume of current trends.
John R. Helliwell +2 more
doaj +2 more sources
Probing laser-driven surface and subsurface dynamics via grazing-incidence XFEL scattering and diffraction [PDF]
We demonstrate a grazing-incidence X-ray platform that simultaneously records time-resolved grazing-incidence small-angle X-ray scattering (GISAXS) and grazing-incidence X-ray diffraction (GID) from a femtosecond-laser-irradiated gold film above the ...
Lisa Randolph +36 more
doaj +2 more sources
Thinner than a knife's edge: 3D-printed liquid sheet jet technology for solution phase XFEL experiments [PDF]
In this commentary, we explore the pioneering implementation of 3D-printed thin liquid sheet devices for advanced X-ray scattering and spectroscopy experiments at high-repetition rate XFELs.
Martin Trebbin
doaj +2 more sources
High-quality ultra-fast total scattering and pair distribution function data using an X-ray free-electron laser [PDF]
High-quality total scattering data, a key tool for understanding atomic-scale structure in disordered materials, require stable instrumentation and access to high momentum transfers. This is now routine at dedicated synchrotron instrumentation using high-
Adam F. Sapnik +50 more
doaj +2 more sources
Coaxial helium electrospray for single-particle imaging at X-ray free electron lasers [PDF]
Single-particle imaging at X-ray free-electron lasers relies on suitable sample injection of nanoscale macromolecules and particles into the gas phase at room temperature.
Safi Rafie-Zinedine +3 more
doaj +2 more sources
Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan +11 more
doaj +1 more source
Artificial intelligence for online characterization of ultrashort X-ray free-electron laser pulses
X-ray free-electron lasers (XFELs) as the world’s brightest light sources provide ultrashort X-ray pulses with a duration typically in the order of femtoseconds.
Kristina Dingel +13 more
doaj +1 more source
3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in ...
Patrick E. Konold +27 more
doaj +1 more source
Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers
With time-resolved crystallography (TRX), it is possible to follow the reaction dynamics in biological macromolecules by investigating the structure of transient states along the reaction coordinate.
Suraj Pandey +2 more
doaj +1 more source
Advances in long-wavelength native phasing at X-ray free-electron lasers
Long-wavelength pulses from the Swiss X-ray free-electron laser (XFEL) have been used for de novo protein structure determination by native single-wavelength anomalous diffraction (native-SAD) phasing of serial femtosecond crystallography (SFX) data.
Karol Nass +35 more
doaj +1 more source

