Results 21 to 30 of about 4,343 (231)

Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX

IUCrJ, 2022
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato   +11 more
doaj   +1 more source

Compact double-bunch x-ray free electron lasers for fresh bunch self-seeding and harmonic lasing

Physical Review Accelerators and Beams, 2017
This paper presents a novel method to improve the longitudinal coherence, efficiency and maximum photon energy of x-ray free electron lasers (XFELs). The method is equivalent to having two separate concatenated XFELs.
C. Emma, Y. Feng, D. C. Nguyen, A. Ratti, C. Pellegrini   +4 more
doaj   +1 more source

The new XFELs [PDF]

Nature Methods, 2018
New X-ray free-electron (XFEL) facilities will broaden access to this technology, facilitate methods development, and push boundaries in structural biology.
openaire   +1 more source

Gold Standard for macromolecular crystallography diffraction data

IUCrJ, 2020
Macromolecular crystallography (MX) is the dominant means of determining the three-dimensional structures of biological macromolecules. Over the last few decades, most MX data have been collected at synchrotron beamlines using a large number of different
Herbert J. Bernstein, Andreas Förster, Asmit Bhowmick, Aaron S. Brewster, Sandor Brockhauser, Luca Gelisio, David R. Hall, Filip Leonarski, Valerio Mariani, Gianluca Santoni, Clemens Vonrhein, Graeme Winter   +11 more
doaj   +1 more source

Velocity bunching at the European XFEL [PDF]

2007 IEEE Particle Accelerator Conference (PAC), 2007
This paper explores the possibility to employ velocity bunching [1] in the first RF module of the European XFEL [2] (referred to as XFEL in this paper) to increase the peak current at the injector exit. The current increase will reduce the total longitudinal bunch compression factor and loosen rf jitter tolerances by the same amount.
Beutner, B., Decking, W., Dohlus, M., Floettmann, K., Krasilnikov, M., Limberg, T.   +5 more
openaire   +2 more sources

3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers

IUCrJ, 2023
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in ...
Patrick E. Konold, Tong You, Johan Bielecki, Joana Valerio, Marco Kloos, Daniel Westphal, Alfredo Bellisario, Tej Varma Yenupuri, August Wollter, Jayanath C. P. Koliyadu, Faisal H.M. Koua, Romain Letrun, Adam Round, Tokushi Sato, Petra Mészáros, Leonardo Monrroy, Jennifer Mutisya, Szabolcs Bódizs, Taru Larkiala, Amke Nimmrich, Roberto Alvarez, Patrick Adams, Richard Bean, Tomas Ekeberg, Richard A. Kirian, Andrew V. Martin, Sebastian Westenhoff, Filipe R. N. C. Maia   +27 more
doaj   +1 more source

Use of diamond sensors for a high-flux, high-rate X-ray pass-through diagnostic

Journal of Synchrotron Radiation, 2022
X-ray free-electron lasers (XFELs) deliver pulses of coherent X-rays on the femtosecond time scale, with potentially high repetition rates. While XFELs provide high peak intensities, both the intensity and the centroid of the beam fluctuate strongly on a
J. Bohon, E. Gonzalez, C. Grace, C. T. Harris, B. Jacobsen, S. Kachiguine, D. Kim, J. MacArthur, F. Martinez-McKinney, S. Mazza, M. Nizam, N. Norvell, R. Padilla, E. Potter, T. Prakash, E. Prebys, E. Ryan, B. A. Schumm, J. Smedley, D. Stuart, M. Tarka, I. S. Torrecilla, M. Wilder, D. Zhu   +23 more
doaj   +1 more source

XFELs for structure and dynamics in biology [PDF]

IUCrJ, 2017
The development and application of the free-electron X-ray laser (XFEL) to structure and dynamics in biology since its inception in 2009 are reviewed. The research opportunities which result from the ability to outrun most radiation-damage effects are outlined, and some grand challenges are suggested.
openaire   +4 more sources

Molecular filming: A director's grammar for visualizing chemistry in motion

Bulletin of the Korean Chemical Society, EarlyView.
Molecular filming names the practice, not just the product, of ultrafast structural science. In deliberate analogy to molecular editing, which rewrites connectivity in space, molecular filming records geometry in time, assembling time‐ordered structural frames into a movie of atomic motion and recasting the field as a grammar of directorial choices ...
Hyotcherl Ihee
wiley   +1 more source

Improvement of photon energy at X-ray free-electron lasers using plasma-based afterburner

Matter and Radiation at Extremes
X-ray free-electron lasers (XFELs) can generate bright X-ray pulses with short durations and narrow bandwidths, leading to extensive applications in many disciplines such as biology, materials science, and ultrafast science.
Letian Liu, Qianyi Ma, Yuhui Xia, Zhenan Wang, Yuekai Chen, Zhiyan Yang, Dongchi Cai, Zewei Xu, Ziyao Tang, Jianghao Hu, Weiming An, Chao Feng, Xueqing Yan, Xinlu Xu   +13 more
doaj   +1 more source