Results 11 to 20 of about 1,584 (183)

The Gamification of XFEL Education Using XFEL Crystal Blaster

Crystals, 2022
Novel groundbreaking techniques, such as serial femtosecond crystallography (SFX), which utilizes X-ray free-electron lasers (XFELs), have led to impressive advances in the field of structural biology. However, educating the next generation of scientists on this complex, advanced, and continuously evolving field can be challenging.
Fiacre Kabayiza, Sarah B. Woodruff, William J. Bauer   +2 more
openaire   +2 more sources

Single-particle imaging by x-ray free-electron lasers—How many snapshots are needed?

Structural Dynamics, 2020
X-ray free-electron lasers (XFELs) open the possibility of obtaining diffraction information from a single biological macromolecule. This is because XFELs can generate extremely intense x-ray pulses that are so short that diffraction data can be ...
I. Poudyal, M. Schmidt, P. Schwander
doaj   +1 more source

Microsecond hydrodynamic interactions in dense colloidal dispersions probed at the European XFEL

IUCrJ, 2021
Many soft-matter systems are composed of macromolecules or nanoparticles suspended in water. The characteristic times at intrinsic length scales of a few nanometres fall therefore in the microsecond and sub-microsecond time regimes.
Francesco Dallari, Avni Jain, Marcin Sikorski, Johannes Möller, Richard Bean, Ulrike Boesenberg, Lara Frenzel, Claudia Goy, Jörg Hallmann, Yoonhee Kim, Irina Lokteva, Verena Markmann, Grant Mills, Angel Rodriguez-Fernandez, Wojciech Roseker, Markus Scholz, Roman Shayduk, Patrik Vagovic, Michael Walther, Fabian Westermeier, Anders Madsen, Adrian P. Mancuso, Gerhard Grübel, Felix Lehmkühler   +23 more
doaj   +1 more source

FAST-XPD: XFEL photon pulses database for modeling XFEL experiments [PDF]

AIP Conference Proceedings, 2019
Knowledge of different properties of the radiation from X-ray FEL is very important for planning experiments. An understanding of such properties can come from start-to-end simulations of experiments: modern FEL simulation allows to reliably predict the output radiation pulses from X-ray FEL.
Manetti, Maurizio, Buzmakov, Alexey, Samoylova, Liubov, Schneidmiller, Evgeny, Sinn, Harald, Szuba, Janusz, Wrona, Krzysztof, Yurkov, Mikhail   +7 more
openaire   +2 more sources

Unsupervised learning approaches to characterizing heterogeneous samples using X-ray single-particle imaging

IUCrJ, 2022
One of the outstanding analytical problems in X-ray single-particle imaging (SPI) is the classification of structural heterogeneity, which is especially difficult given the low signal-to-noise ratios of individual patterns and the fact that even ...
Yulong Zhuang, Salah Awel, Anton Barty, Richard Bean, Johan Bielecki, Martin Bergemann, Benedikt J. Daurer, Tomas Ekeberg, Armando D. Estillore, Hans Fangohr, Klaus Giewekemeyer, Mark S. Hunter, Mikhail Karnevskiy, Richard A. Kirian, Henry Kirkwood, Yoonhee Kim, Jayanath Koliyadu, Holger Lange, Romain Letrun, Jannik Lübke, Abhishek Mall, Thomas Michelat, Andrew J. Morgan, Nils Roth, Amit K. Samanta, Tokushi Sato, Zhou Shen, Marcin Sikorski, Florian Schulz, John C. H. Spence, Patrik Vagovic, Tamme Wollweber, Lena Worbs, P. Lourdu Xavier, Oleksandr Yefanov, Filipe R. N. C. Maia, Daniel A. Horke, Jochen Küpper, N. Duane Loh, Adrian P. Mancuso, Henry N. Chapman, Kartik Ayyer   +41 more
doaj   +1 more source

Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature

IUCrJ, 2022
Room-temperature macromolecular crystallography allows protein structures to be determined under close-to-physiological conditions, permits dynamic freedom in protein motions and enables time-resolved studies.
Tadeo Moreno-Chicano, Leiah M. Carey, Danny Axford, John H. Beale, R. Bruce Doak, Helen M. E. Duyvesteyn, Ali Ebrahim, Robert W. Henning, Diana C. F. Monteiro, Dean A. Myles, Shigeki Owada, Darren A. Sherrell, Megan L. Straw, Vukica Šrajer, Hiroshi Sugimoto, Kensuke Tono, Takehiko Tosha, Ivo Tews, Martin Trebbin, Richard W. Strange, Kevin L. Weiss, Jonathan A. R. Worrall, Flora Meilleur, Robin L. Owen, Reza A. Ghiladi, Michael A. Hough   +25 more
doaj   +1 more source

Compact double-bunch x-ray free electron lasers for fresh bunch self-seeding and harmonic lasing

Physical Review Accelerators and Beams, 2017
This paper presents a novel method to improve the longitudinal coherence, efficiency and maximum photon energy of x-ray free electron lasers (XFELs). The method is equivalent to having two separate concatenated XFELs.
C. Emma, Y. Feng, D. C. Nguyen, A. Ratti, C. Pellegrini   +4 more
doaj   +1 more source

Preferred orientation and its effects on intensity-correlation measurements

IUCrJ, 2022
Intensity-correlation measurements allow access to nanostructural information on a range of ordered and disordered materials beyond traditional pair-correlation methods.
Jack Binns, Connie Darmanin, Cameron M. Kewish, Sachini Kadaoluwa Pathirannahalge, Peter Berntsen, Patrick L. R. Adams, Stefan Paporakis, Daniel Wells, Francisco Gian Roque, Brian Abbey, Gary Bryant, Charlotte E. Conn, Stephen T. Mudie, Adrian M. Hawley, Timothy M. Ryan, Tamar L. Greaves, Andrew V. Martin   +16 more
doaj   +1 more source

The structure of tick-borne encephalitis virus determined at X-ray free-electron lasers. Simulations

Journal of Synchrotron Radiation, 2023
The study of virus structures by X-ray free-electron lasers (XFELs) has attracted increased attention in recent decades. Such experiments are based on the collection of 2D diffraction patterns measured at the detector following the application of ...
Dameli Assalauova, Ivan A. Vartanyants
doaj   +1 more source

The new XFELs [PDF]

Nature Methods, 2018
New X-ray free-electron (XFEL) facilities will broaden access to this technology, facilitate methods development, and push boundaries in structural biology.
openaire   +1 more source