Results 111 to 120 of about 173,386 (236)

Label-free single-particle imaging approach for ultra-rapid detection of pathogenic bacteria in clinical samples. [PDF]

Proc Natl Acad Sci U S A, 2022
Chen S, Su YW, Sun J, Chen T, Zheng Y, Sui LJ, Yang S, Liu C, Wang P, Li T, Chi Q, Sun H, Chen J, Xu BQ, Huang Z, Fang Y.   +15 more
europepmc   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Oligo DNA-based quantum dot (QD) single-particle tracking for multicolor single-molecule imaging

Biophysics and Physicobiology
Quantum dot single-particle tracking (QD-SPT), a powerful tool for analyzing membrane domains that are critical to various cellular processes, is widely used in membrane molecular dynamics research.
Shigeo Sakuragi, Naoki Kato, Tomoya Uchida, Boxiao Zhao, Taro Katagiri, Miyu Enomoto, Rie Kato, Hideaki Yoshimura, Chisato Oyama, Iona Katayama, Ayano Chikuma, Yuji Teramura, Hiroko Bannai   +12 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Expected resolution limits of x-ray free-electron laser single-particle imaging for realistic source and detector properties. [PDF]

Struct Dyn, 2022
E J, Kim Y, Bielecki J, Sikorski M, de Wijn R, Fortmann-Grote C, Sztuk-Dambietz J, Koliyadu JCP, Letrun R, Kirkwood HJ, Sato T, Bean R, Mancuso AP, Kim C.   +13 more
europepmc   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Single particle fluorescence imaging of perovskite nanocrystal crystallization for illustrating coupled nucleation-and-growth

Nature Communications
Because of the lack of spatiotemporal characterization techniques, it has been of great challenge to investigate the crystallization of nanocrystals.
Lige Liu, Dashan Dong, Zhiwei Long, Wanxue Wei, Chang Sun, Wei Liu, Xiaoshuai Huang, Liangyi Chen, Haizheng Zhong, Kebin Shi   +9 more
doaj   +1 more source

Erratum: An advanced workflow for single-particle imaging with the limited data at an X-ray free-electron laser. Corrigendum. [PDF]

IUCrJ, 2022
Assalauova D, Kim YY, Bobkov S, Khubbutdinov R, Rose M, Alvarez R, Andreasson J, Balaur E, Contreras A, DeMirci H, Gelisio L, Hajdu J, Hunter MS, Kurta RP, Li H, McFadden M, Nazari R, Schwander P, Teslyuk A, Walter P, Xavier PL, Yoon CH, Zaare S, Ilyin VA, Kirian RA, Hogue BG, Aquila A, Vartanyants IA.   +27 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Cross-calibration of multiple optical instruments for the measurement of particle size distributions in water

Frontiers in Marine Science
Particle size spectra, describing particle abundance as a function of size, are essential for understanding marine ecosystem structure and biogeochemical processes. The slopes of size spectra provide insights into ecosystem characteristics.
Marika Takeuchi, Zonghua Liu, Zonghua Liu, Will Major, Yéssica Vanessa Contreras-Pacheco, Thangavel Thevar, Jack Rees Williams, Sarah Lou Carolin Giering   +7 more
doaj   +1 more source