Results 51 to 60 of about 2,116,123 (314)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

An experimental approach to heat loss measurement of horizontal two-phase flow boiling in low-pressure low-flow (LPLF) conditions

Case Studies in Thermal Engineering
A crucial parameter remarkably influencing the reliability and accuracy of vapor quality measurements in flow boiling experiments is the measurement of heat loss.
Mehdi Kabir
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Verification benchmarks for single-phase flow in three-dimensional fractured porous media [PDF]

Advances in Water Resources, 2020
I. Berre, W. Boon, B. Flemisch, A. Fumagalli, D. Gläser, E. Keilegavlen, A. Scotti, Ivar Stefansson, A. Tatomir, K. Brenner, Samuel Burbulla, P. Devloo, O. Durán, M. Favino, Julian Hennicker, I.-Hsien Lee, K. Lipnikov, R. Masson, K. Mosthaf, M. Nestola, C. Ni, K. Nikitin, Philipp Schädle, D. Svyatskiy, Ruslan M. Yanbarisov, P. Zulian   +25 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Single- and two-phase flow model in low-permeability reservoir

Petroleum, 2019
In petroleum development, low-permeability reservoir means having permeability of porous media lower than 50 micro-Darcy. The mathematical model of liquid flow in low-permeability reservoirs has been difficult to describe for a long time, and an ideal ...
Song Fuquan, Song Xingxing, Wang Yong, Sun Yeheng   +3 more
doaj   +1 more source

Local thermodynamic description of isothermal single-phase flow in porous media [PDF]

, 2022
Olav Galteland, Michael T. Rauter, Mina S. Bratvold, Thuat T. Trinh, Dick Bedeaux, Signe Kjelstrup   +5 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Investigation on the Handling Ability of Centrifugal Pumps under Air–Water Two-Phase Inflow: Model and Experimental Validation

Energies, 2018
The paper presents experimental and numerical investigations performed on a single stage, single-suction, horizontal-orientated centrifugal pump in air–water two-phase non-condensable flow conditions.
Qiaorui Si, Gérard Bois, Qifeng Jiang, Wenting He, Asad Ali, Shouqi Yuan   +5 more
doaj   +1 more source