Results 71 to 80 of about 12,921,630 (316)

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Single-Cell-Derived Tumor-Sphere Formation and Drug-Resistance Assay Using an Integrated Microfluidics

, 2019
Considerable evidence points to cancer stem-like cells (CSCs) as responsible for promoting progression, metastasis, and drug resistance. Without damage to the cell biological properties, single-cell-derived tumor-sphere is encouraging options for CSCs ...
Jing Ding, Long Pang (457760), Long Pang, Jianglin Fan (448849), Yuxin Ge, Yuxin Ge (5988779), Shih-Kang Fan (733610), Jianglin Fan, Shih-Kang Fan, Jing Ding (32381)   +9 more
core   +1 more source

Regulation of transcriptional homeostasis by DNA methylation upon genome duplication in pak choi

Molecular Horticulture
Polyploidy occurs frequently in plants and is an important force in plant evolution and crop breeding. New polyploids face various challenges due to genome duplication and subsequent changes in epigenetic modifications, nucleus/cell size and gene ...
Min Ma, Yuanda Wang, Zhenfei Sun, Ranze Zhao, Honghua Li, Xiaoxuan Li, Hongfang Zhu, Xuedong Yang, Changwei Zhang, Yuda Fang   +9 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Deconstructing olfactory stem cell trajectories at single-cell resolution [PDF]

, 2017
A detailed understanding of the paths that stem cells traverse to generate mature progeny is vital for elucidating the mechanisms governing cell fate decisions and tissue homeostasis. Adult stem cells maintain and regenerate multiple mature cell lineages
Ngai, John, Nir Yosef, Yoon Gi Choi, Gadye, Levi, Purdom, Elizabeth, Wagner, Allon, Choi, Yoon Gi, Risso, Davide, Michael B. Cole, Levi Gadye, Ariane Baudhuin, Quetzal Flores, Fletcher, Russell B, Davide Risso, Street, Kelly N, John Ngai, Kelly N. Street, Diya Das, Yosef, Nir, Dudoit, Sandrine, Flores, Quetzal, Baudhuin, Ariane, Sandrine Dudoit, Das, Diya, Elizabeth Purdom, Cole, Michael B, Russell B. Fletcher, Allon Wagner   +27 more
core   +1 more source

An Infrared Actin Probe for Deep-Cell Electroporation-Based Single-Molecule Speckle (eSiMS) Microscopy

Sensors, 2017
Single-molecule speckle (SiMS) microscopy is a powerful method to directly elucidate biochemical reactions in live cells. However, since the signal from an individual fluorophore is extremely faint, the observation area by epi-fluorescence microscopy is ...
Sawako Yamashiro, Naoki Watanabe
doaj   +1 more source

Tumor microenvironment-responsive DNA-based nanomedicine triggers innate sensing for enhanced immunotherapy

Journal of Nanobiotechnology, 2023
Lack of proper innate sensing inside the tumor microenvironment could reduce both innate and adaptive immunity, which remains a critical cause of immunotherapy failure in various tumor treatments.
Jinyang Li, Xiaoyu Han, Shanshan Gao, Yumeng Yan, Xiaoguang Li, Hui Wang   +5 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Lu mouse fetal liver 2021

, 2023
Dataset published by Lu et al. 2021, which contains single-cell RNA sequencing data of E14.5 whole fetal liver cells and MERFISH data from four wild type E14.5 fetal mouse livers measuring hematopoietic stem cell (HSC) niches in 140 images. Citation Lu,
Single-cell best practices (14656733)
core   +1 more source

Overview of Single-Molecule Speckle (SiMS) Microscopy and Its Electroporation-Based Version with Efficient Labeling and Improved Spatiotemporal Resolution

Sensors, 2017
Live-cell single-molecule imaging was introduced more than a decade ago, and has provided critical information on remodeling of the actin cytoskeleton, the motion of plasma membrane proteins, and dynamics of molecular motor proteins. Actin remodeling has
Sawako Yamashiro, Naoki Watanabe
doaj   +1 more source