Results 61 to 70 of about 12,921,630 (316)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Luecken Cite-seq human bone marrow 2021 preprocessing

, 2023
Dataset published by Luecken et al. 2021 which contains data from human bone marrow measured through joint profiling of single-nucleus RNA and Antibody-Derived Tags (ADTs) using the 10X 3' Single-Cell Gene Expression kit with Feature Barcoding in ...
Single-cell best practices (14656733)
core   +1 more source

Identification and characterization of planarian multinucleated cells in Schmidtea mediterranea using imaging flow cytometry

Frontiers in Cell and Developmental Biology
Cellular polyploidy plays critical roles in both pathological and physiological processes. While extensively studied in organisms like Drosophila and zebrafish, and mammalian tissues such as the liver, kidney and heart, the existence of multinucleated ...
Annasha Dutta, Anna Samelak-Czajka, Magdalena Trybus, Marcin Osuch, Anastasiia Zaremba, Paulina Jackowiak   +5 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

agitter/single-cell-pseudotime: 2018-06-25 archive

, 2018
<p>An overview of algorithms for estimating pseudotime in single-cell RNA-seq data.  Initial archive for Zenodo DOI and citation. Adopting release practices from <a href="https://github.com/seandavi/awesome-single-cell">https ...
Anthony Gitter, Anthony Gitter (142451)
core   +1 more source

Luecken Cite-seq human bone marrow 2021 s4d8

, 2023
Dataset published by Luecken et al. 2021 which contains data from human bone marrow measured through joint profiling of single-nucleus RNA and Antibody-Derived Tags (ADTs) using the 10X 3' Single-Cell Gene Expression kit with Feature Barcoding in ...
Single-cell best practices (14656733)
core   +1 more source

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells [PDF]

, 2021
B cell responses are critical for antiviral immunity. However, a comprehensive picture of antigen-specific B cell differentiation, clonal proliferation, and dynamics in different organs after infection is lacking. Here, by combining single-cell RNA and B
Greiff, Victor,, Borcherding, Nicholas, Bernasconi, Valentina, Lebrero-Fern\ue1ndez, Cristina, Smirnov, Ilya, Lebrero-Fernández, Cristina,, Mathew, Nimitha R.,, Schön, Karin,, Nakka, Sravya S.,, Jayanthan, Jayalal K., Yewdell, Jonathan W.,, Lebrero-Fernández, Cristina, Axelsson, Hannes, Yewdell, Jonathan W., Robinson, Jonathan, Rodin, William, Czarnewski, Paulo, Greiff, Victor, Angeletti, Davide,, Harandi, Ali M., Kalathilparambil Jayanthan, Jayalal, Rodin, William,, Robinson, Jonathan,, Bernasconi, V.,, Borcherding, Nicholas,, Axelsson, Hannes,, Lycke, Nils, Robinson, Jonathan L., Czarnewski, Paulo,, Angeletti, Davide, Sch\uf6n, Karin, Bernasconi, V., Smirnov, Ilya V., Smirnov, Ilya V.,, Lycke, N. Y.,, Yewdell, William T.,, Bemark, Mats, Nakka, Sravya S., Schön, Karin, Lycke, Nils Y., Yewdell, William T., Emmanouilidi, Aikaterini, Lycke, N. Y., Mathew, Nimitha R., Harandi, A. M., Bemark, Mats,, Harandi, A. M.,, Emmanouilidi, Aikaterini,, Jayanthan, Jayalal K.,   +48 more
core   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Luecken multiome human bone marrow 2021 s4d8

, 2023
Dataset published by Luecken et al. 2021 which contains data from human bone marrow measured through joint profiling of single-nucleus RNA and chromatin accessibility using the 10X Genomics Single Cell Multiome ATAC + Gene Expression Kit.
Single-cell best practices (14656733)
core   +1 more source

Powerful and accurate detection of temporal gene expression patterns from multi-sample multi-stage single-cell transcriptomics data with TDEseq

Genome Biology
We present a non-parametric statistical method called TDEseq that takes full advantage of smoothing splines basis functions to account for the dependence of multiple time points in scRNA-seq studies, and uses hierarchical structure linear additive mixed ...
Yue Fan, Lei Li, Shiquan Sun
doaj   +1 more source