Results 31 to 40 of about 7,974,201 (245)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

On the experience and evidence about mixing modes of data collection in large-scale surveys where the web is used as one of the modes in data collection [PDF]

, 2011
This paper presents experience and evidence, from international sources, of the effects on survey quality of the use of mixed modes in data collection, where the web is used as one of the modes.
Gumy, Julia M, Gumy, Julia M., Dex, Shirley, Gumy, Julia   +3 more
core  

Single-photon circularly polarized single-mode vortex beams

, 2023
Generation of single photons carrying spin and orbital angular momenta (SAM and OAM) opens enticing perspectives for exploiting multiple degrees of freedom for high-dimensional quantum systems.
Changying Zhao (5990135), Danylo Komisar (11105128), Xujing Liu (12467659), Sergey I. Bozhevolnyi (1466827), Yinhui Kan (8728011), Shailesh Kumar (441797)   +5 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Inverse scattering designs of dispersion-engineered single-mode planar waveguides

We use an inverse-scattering (IS) approach to design single-mode waveguides with controlled linear and higher-order dispersion. The technique is based on a numerical solution to the Gelfand-Levitan-Marchenko integral equation, for the inversion of ...
Poletti, F., May, A.R., Zervas, M.N.
core   +1 more source

How to control the laser emission in single longitudinal mode [PDF]

, 2015
Producción CientíficaIn the pictures we show the interference patterns obtained with a solid Fabry-Perot etalon with the 532 nm radiation emitted by a Nd:YAG laser. In Fig. A using a seed laser, this means, only one longitudinal mode. In Fig.
Pérez Callejo, Gabriel, Fuentes García, Luis María, González Fernández, Verónica, Vasallo, E., Rosa García, María Inmaculada de la, Grützmacher, K., Pérez, C.   +6 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Quasi-single mode operated few-mode fiber for distributed acoustic sensing

, 2019
We experimentally report a proof-of-concept demonstration of a few-mode fiber (FMF) based distributed acoustic sensor (DAS) design, aiming at upgrading the capabilities of the typical DAS that employs the standard single mode fiber (SMF).
Frode Hveding, Muhammad Arsalan, Yuan Mao, Ashry, Islam, Ng, Tien Khee, Hveding, Frode, Boon S. Ooi, Mao, Yuan, Ooi, Boon S., Islam Ashry, Arsalan, Muhammad, Tien Khee Ng   +11 more
core   +1 more source

A waveguide polarization toolset design based on mode beating [PDF]

, 2011
A toolset of waveguide elements is examined, which can be combined to produce polarization functional devices in a single contiguous waveguide. In particular, waveguide implementations of an optical isolator and a polarization modulator are discussed ...
Hutchings, D.C., David C Hutchings, Barry M Holmes, Holmes, B.M.   +3 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source