Results 71 to 80 of about 149,462 (299)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Single longitudinal mode selection of high power actively Q-switched lasers

, 1972
A Pockels cell Q-switch has been operated in a manner analogous to a saturable absorber by initially keeping the cell partly open for the first 1000 or so double passes and then opening it completely at a pre-set resonator power.
Hanna, D.C., Smith, R.C., Luther-Davies, B.   +2 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

S-band single-longitudinal-mode erbium-doped fiber ring laser with ultra-narrow linewidth, ultra-high OSNR, high stability and low RIN

, 2021
A high-performance S-band single-longitudinal-mode (SLM) erbium-doped fiber (EDF) ring cavity laser based on a depressed cladding EDF is investigated and experimentally demonstrated.
Kuanlin Mu (14384802), Zhengkang Wang (14384796), Jianming Shang (14384799), Song Yu (3073554), Yaojun Qiao (14384805), Siqiao Li (6383837)   +5 more
core   +1 more source

Transverse stress rupture properties of a third generation single crystal superalloy at medium and elevated temperatures

Cailiao gongcheng, 2020
At the conditions of 760℃/800 MPa, 980℃/250 MPa and 1100℃/137 MPa, the transv-erse stress rupture properties of a nickel-based third generation single crystal superalloy were investigated.
YANG Wan-peng, LI Jia-rong, LIU Shi-zhong, ZHAO Jin-qian, SHI Zhen-xue, WANG Xiao-guang   +5 more
doaj   +1 more source

Intensity fluctuations in longitudinal modes of a nearly single-mode AlGaAs laser

Electronics Letters, 1982
The behaviour of the relative intensity noise in each longitudinal mode of a CW DH AlGaAs laser exhibiting mode jumps is observed and theoretically explained. The stabilisation of the amplitude fluctuations of the main mode due to the gain saturation which could be expected when the injection current increases is cancelled by the shift of the maximum ...
I. Joindot, C. Boisrobert
openaire   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Single-longitudinal-mode operation from a semiconductor laser array via feedback from a modified collimating objective

, 1990
A technique for obtaining single-longitudinal-mode collimated output from a ten-stripe laser diode array using feedback from a single modified microscope objective is described.
MacCormack, S., Eason, R.W.
core   +1 more source

High average power nanosecond pulsed single longitudinal mode diamond Raman laser in the 1.6 µm waveband

Functional Diamond
Realizing high average power nanosecond pulsed single longitudinal mode laser sources around 1.6 μm are of intense interest for applications as diverse as range finding, remote sensing, and environmental monitoring.
Weifeng Tan, Yisen Wang, Peining Chen, Rongzhuo Chen, Siqi Zhu, Hao Yin, Zhen Li, Zhenqiang Chen, Shibo Dai   +8 more
doaj   +1 more source