Results 61 to 70 of about 149,462 (299)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Wavelength-Switchable Single-Longitudinal- Mode Thulium-Doped Fiber Laser With Sampled Fiber Bragg Grating

open access: yesIEEE Access, 2021
A wavelength-switchable single-longitudinal-mode thulium-doped fiber laser using a sampled fiber Bragg grating is proposed in this study. The laser can be switched between three single-wavelength and three dual-wavelength modes of operation.
Wenguo Han   +9 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

High Q Lateral-Field-Excited Bulk Resonator Based on Single-Crystal LiTaO₃ for 5G Wireless Communication

open access: yesIEEE Journal of the Electron Devices Society, 2021
The paper presents the design and fabrication of lateral-field-excited (LFE) resonators based on 42° Y-cut single-crystal LiTaO3 (LT) on silicon dioxide (SiO2).
Yanmei Xue   +4 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Longitudinal mode-coupling instabilities of proton bunches in the CERN Super Proton Synchrotron

open access: yesPhysical Review Accelerators and Beams, 2023
In this paper, we study single-bunch instabilities observed in the CERN Super Proton Synchrotron (SPS). According to the linearized Vlasov theory, radial or azimuthal mode-coupling instabilities result from a coupling of bunch-oscillation modes, which ...
Ivan Karpov
doaj   +1 more source

Impact of Mode Switching on Nonresponse and Bias in a Multimode Longitudinal Study of Young Adults

open access: yesSurvey Research Methods, 2023
Young adults are generally hard to survey, presenting researchers with numerous difficulties. They are hard to locate and contact due to high mobility. They are hard to persuade and exhibit high levels of resistance to survey participation. As a result,
Ting Yan   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Stabilisation of single longitudinal mode operation in a Q-switched Nd:YAG laser [PDF]

open access: yes, 1985
Detection of the reflected laser beam power from the mode-selecting etalon in a prelase-Q-switched laser provides an indicator of mode-frequency drifts.
Hanna, D.C., Wong, K-H., Carr, I.D.
core   +1 more source

All-Polarization Maintaining Single-Longitudinal-Mode Fiber Laser with Ultra-High OSNR, Sub-kHz Linewidth and Extremely High Stability

open access: yes, 2021
An all-polarization maintaining (PM) single-longitudinal-mode (SLM) erbium-doped fiber laser (EDFL) with ultra-high optical signal-to-noise ratio (OSNR), ultra-narrow linewidth and extremely high stability is proposed and experimentally demonstrated.
Kuanlin Mu (14384802)   +5 more
core   +1 more source

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