Results 61 to 70 of about 638,812 (341)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Single longitudinal mode operation of a 3 atm pulsed CO2 laser with hybrid method [PDF]

مجله علوم و فنون هسته‌ای, 2019
In this work, the hybrid configuration was used to produce the single longitudinal mode operation of pulsed CO2 laser with 14 cm long active volume at the pressure 3 atm.
S Kazemi Sangsari, S Jelvani, M Mollabashi, M Ilchi, Z Pourhasannezhad, D Ahadpour, K Silakhori   +6 more
doaj   +1 more source

A tunable S-plus L-band continuous-wave single-longitudinal-mode fiber-optical parametric oscillator [PDF]

, 2011
We demonstrate an all-fiber continuous-wave single-longitudinal-mode fiber-optical parametric oscillator. The output tuning range extends from 1487 to 1541 nm and from 1570 to 1630 nm, which covers the S- and L-bands. Single-longitudinal-mode oscillation
Chui, PC, Wong, KKY, Zhang, C, Zhou, Y
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

990 nm High-Power High-Beam-Quality DFB Laser With Narrow Linewidth Controlled by Gain-Coupled Effect

IEEE Photonics Journal, 2019
High-power single-longitudinal-mode regrowth-free gain-coupled distributed feedback laser diode based on ridge waveguide with periodic current injection is achieved at 990 nm. Our device is fabricated only by standard i-line lithography with micron-scale
Yu-Xin Lei, Yong-Yi Chen, Feng Gao, De-Zheng Ma, Peng Jia, Qiu Cheng, Hao Wu, Chun-Kao Ruan, Lei Liang, Chao Chen, Jun Zhang, Jing-Yu Tian, Li Qin, Yong-Qiang Ning, Li-Jun Wang   +14 more
doaj   +1 more source

Kohn Anomaly in Raman Spectroscopy of Single Wall Carbon Nanotubes

, 2010
Phonon softening phenomena of the $\Gamma$ point optical modes including the longitudinal optical mode, transverse optical mode and radial breathing mode in "metallic" single wall carbon nanotubes are reviewed from a theoretical point of view. The effect
Ando, Ando, Bachilo, Caudal, Das, Deshpande, Dresselhaus, Dubay, Dubay, Eklund, Farhat, Farhat, Hamada, Hootan Farhat, Ishikawa, Jiang, Jorio, Jorio, Jorio, Kane, Katsnelson, Ken-ichi Sasaki, Kleiner, Kohn, Lazzeri, Mildred S. Dresselhaus, Mintmire, Miyake, Nguyen, Ouyang, Park, Pimenta, Piscanec, Popov, Popov, Porezag, Reich, Riichiro Saito, Saito, Saito, Saito, Saito, Saito, Samsonidze, Sasaki, Sasaki, Sasaki, Sasaki, Sasaki, Sasaki, Strano, Suzuura, Yan, Yang, Yang   +54 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Wavelength-Switchable Single-Longitudinal- Mode Thulium-Doped Fiber Laser With Sampled Fiber Bragg Grating

IEEE Access, 2021
A wavelength-switchable single-longitudinal-mode thulium-doped fiber laser using a sampled fiber Bragg grating is proposed in this study. The laser can be switched between three single-wavelength and three dual-wavelength modes of operation.
Wenguo Han, Fengping Yan, Ting Feng, Luna Zhang, Biao Guan, Qi Qin, Ying Guo, Ting Li, Hong Zhou, Yuping Suo   +9 more
doaj   +1 more source

A strategy for delivering high torsionality in longitudinal-torsional ultrasonic devices [PDF]

, 2011
A composite longitudinal-torsional vibration mode has applications in ultrasonic motors, ultrasonic welding and ultrasonic drilling. There are two ways to obtain this vibration behaviour using a single transducer, namely (i) coupling of a longitudinal ...
Al-Budairi, H., Harkness, P., Lucas, M.
core   +1 more source