Results 101 to 110 of about 4,005,529 (300)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Coupled-Mode Theory of Multipath Interference in Quasi-Single Mode Fibers

IEEE Photonics Journal, 2015
We use the power coupled-mode theory to study the interplay between multipath interference (MPI) and differential mode attenuation (DMA) in quasi-single mode (QSM) fibers.
M. Mlejnek, I. Roudas, J. D. Downie, N. Kaliteevskiy, K. Koreshkov   +4 more
doaj   +1 more source

Stability Conditions and the Single Mode Approximation in FQHE

, 1996
A thermodynamic stability criterion for the spontaneous breaking of the translation invariance of many particle systems is derived. It simply requires the positive character of the wavevector dependent dielectric function as generalising the same ...
Alejandro Cabo, Aurora Pérez-Martinez, Cabo, Cabo, Cabo, Chakraborty, Chui, Chui, Dai, Girvin, Landau, Landau, March, March, Perez Martinez, Tesanovic, Willet   +16 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Generating single-mode behavior in fiber-coupled optical cavities

, 2010
We propose to turn two resonant distant cavities effectively into one by coupling them via an optical fiber which is coated with two-level atoms [Franson et al., Phys. Rev. A 70, 062302 (2004)].
Almut Beige, H. Carmichael, Jonathan Busch, W. Vogel   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys

Survey Research Methods, 2013
Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj   +1 more source

Toward a compact fibered squeezing parametric source

, 2018
In this work, we investigate three different compact fibered systems generating vacuum squeezing that involve optical cavities limited by the end surface of a fiber and by a curved mirror and containing a thin parametric crystal.
Brieussel, Alexandre, Fabre, Claude, Joos, Maxime, Ott, Konstantin, Treps, Nicolas   +4 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source