Results 111 to 120 of about 1,357,497 (310)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Coupled-Mode Theory of Multipath Interference in Quasi-Single Mode Fibers
We use the power coupled-mode theory to study the interplay between multipath interference (MPI) and differential mode attenuation (DMA) in quasi-single mode (QSM) fibers.
M. Mlejnek +4 more
doaj +1 more source
Large mode area fibers are imperative for scaling up the average power of fiber lasers. Single-mode behavior and low FM loss are the crucial functionalities for these fibers.
Baskiotis, C. +3 more
core +1 more source
Wang-Single-mode sapphire fiber Bragg grating Fig7d.csv
"Single-mode sapphire fiber Bragg grating" Data File 5 (Underlying data for Figure 7d) Measured reflection spectrum of a sapphire waveguide Bragg ...
Frank Payne (11688151) +6 more
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys
Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Single-mode coherent synchrotron radiation instability
The microwave instability driven by the coherent synchrotron radiation (CSR) has been previously studied [S. Heifets and G. V. Stupakov, Phys. Rev. ST Accel.
S. Heifets, G. Stupakov
doaj +1 more source
Single Transverse Whispering-Gallery Mode AlGaInAs/InP Hexagonal Resonator Microlasers
AlGaInAs/InP hexagonal resonator microlasers with an output waveguide connected to one vertex of the hexagon are fabricated using standard photolithography and inductively coupled plasma (ICP) etching process.
J. D. Lin +6 more
doaj +1 more source

