Results 131 to 140 of about 1,357,497 (310)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Bulged CH3NH3PbBr3 Microwires for Single‐Mode Lasing
Herein, the lasing action of fabricated bulged CH3NH3PbBr3 microwires is demonstrated with features of a low threshold, narrow linewidth, single‐mode operation, and high intensity.
Wanling Wu +8 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
In this paper, a temperature sensing scheme with a miniature MZI structure based on the principle of inter-mode interference is proposed. The sensing structure mainly comprises single mode–coreless–multimode–coreless–single mode fibers (SCMCSs), which ...
Qing Yang +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Semiconductor filled microstructured optical fibres with single mode guidance
Microstructured optical fibre (MOF) technology has generated new opportunities for the implementation of optical fibres with novel properties and functions [1].
Vukovic, N. +3 more
core
External cavity mode structure of a two-mode VCSEL subject to optical feedback
We consider a multi-transverse-mode vertical-cavity surface-emitting laser (VCSEL) subject to optical feedback. The system is modeled by a partial differential equation for the spatial carrier population, which is coupled to delay differential equations ...
Green, K +5 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

