Results 91 to 100 of about 1,178,188 (315)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The nature of condensed single molecules : local electronic and mechanical characteristics [PDF]

open access: yes, 2014
In order to advance the performance of molecule based electronic devices a detailed and fundamental knowledge about the underlying physical aspects is mandatory.
Fremy, Sweetlana Deva
core   +1 more source

Single-Component Molecule-Based Ferrimagnetics

open access: yes, 2016
Single-Component Molecule-Based ...
Takayasu Kanaya (2987190)   +5 more
core   +3 more sources

Single‐Molecule Conductance of Staffanes [PDF]

open access: yesAngewandte Chemie International Edition
Abstract We report the first conductance measurements of [ n ]staffane (bicyclopentane) oligomers in single‐molecule junctions. Our studies reveal two quantum transport characteristics unique to staffanes that emerge from their strained bicyclic structure.
Ashley Pimentel   +3 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Single-molecule-resolution ultrafast near-field optical microscopy via plasmon lifetime extension

open access: yes, 2020
A recent study shows that: when a long lifetime particle is positioned near a plasmonic metal nanoparticle, lifetime of plasmon oscillations extends, but, "only" near that long-life particle [PRB 101, 035416 (2020)].
Ramazan Sahin (14358723)   +3 more
core   +1 more source

Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]

open access: yes, 2008
The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Versatile Control System for Automated Single-Molecule Optical Tweezers Investigations

open access: yes, 2010
We present a versatile control system to automate single-molecule biophysics experiments. This method combines low-level controls into various functional, user-configurable modules, which can be scripted in a domain-specific instruction language.
Steven J. Koch, Richard C. Yeh
core  

Single-Molecule-Based Detection of Conserved Influenza A Virus RNA Promoter Using a Protein Nanopore

open access: yes, 2019
Influenza A viruses (IAVs) cause annual epidemic and severe pandemic outbreaks worldwide and result in high mortality. Despite the importance of surveillance for preventing IAV infection, the existing techniques are inefficient for ultrasensitive ...
Sohee Oh (46468)   +5 more
core   +1 more source

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