Results 81 to 90 of about 1,178,188 (315)

Single‐Molecule Electronic Biosensors: Principles and Applications

Advanced Sensor Research, 2023
Single‐biomolecule electronic sensing techniques are of great importance in many fields, from medical diagnosis to disease surveillance. As the physiological changes of single biomolecules can be converted into measurable electrical signals, single ...
Xinyue Chang, Yani Huo, Cong Zhao, Wanqi Sun, Ziqi Song, Ziyuan Qi, Jinying Wang, Chuancheng Jia, Xuefeng Guo   +8 more
doaj   +1 more source

Single-molecule peptide fingerprinting [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Protein sequencing remains a challenge for small samples. A sensitive sequencing technology will create the opportunity for single-cell proteomics and real-time screening for on-site medical diagnostics. To resolve protein identity, we previously developed a computational algorithm that analyzes the ordered sequence of ...
Jetty van Ginkel, Mike Filius, Malwina Szczepaniak, Pawel Tulinski, Anne S. Meyer, Chirlmin Joo   +5 more
openaire   +3 more sources

Effectiveness of a Novel Low‐Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb‐Threatening Ischemia: A Single‐Center Retrospective Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka, Takayasu Ohtake, Kei Ohmori, Chika Shibuya, Tomoki Tsukahara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Yusuke Tsukamoto, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi   +12 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Introduction to single molecule analysis and computation: the FOCUS Project

, 2014
The FP7 project FOCUS “Single-molecule activation and detection” belongs to the FET Proactive 7 Programme: “Molecular Scale Devices and Systems” and is aimed at investigating and developing molecular devices (MD) where single molecules become computing ...
Vincent Torre, Torre, Vincent, Mazzolini, Monica, Monica Mazzolini   +3 more
core   +1 more source

Electrofluorochromism at the single-molecule level [PDF]

Science, 2018
Changing emission with charge states The fluorescence of electrochromic molecules changes with their charge state. Doppagne et al. studied the optical emission of single zinc-phthalocyanine molecules excited by electron injection from a scanning tunneling microscope tip. The molecules were adsorbed on salt
Benjamin Doppagne, Michael C. Chong, Hervé Bulou, Alex Boeglin, Fabrice Scheurer, Guillaume Schull   +5 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Single Molecule of a π-Conjugated Polymer Slowly Twinkles in Solution at Room Temperature [PDF]

, 2001
A phenylacetylene monomer, 4-(decyloxycarbonyl)phenylacetylene (DecCPA), was synthesized and polymerized by using the combined catalyst system, i.e., [Rh(norbornadiene)Cl]_2 and triethylamine, to give a yellow solid π-conjugated polymer [poly(DecCPA ...
Minami, Hiroshi, Ken-ichi Shinohara, Hiroshi Minami, Higuchi, Hideo, Gen Kato, Hideo Higuchi, Shinohara, Ken-ichi, Kato, Gen   +7 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source