Results 111 to 120 of about 10,451,032 (401)
Examining Sources of Error in PCR by Single-Molecule Sequencing
PLoS ONE, 2017 Next-generation sequencing technology has enabled the detection of rare genetic or somatic mutations and contributed to our understanding of disease progression and evolution.
V. Potapov, J. L. Ong
semanticscholar +1 more source
Single-molecule interfacial electron transfer dynamics manipulated by external electric current
, 2011 Interfacial electron transfer (IET) dynamics in 1,1'-dioctadecyl-3, 3, 3', 3'-tetramethylindodicarbocyanine (DiD) dye molecules / indium tin oxide (ITO) film system have been probed at the ensemble and single-molecule level by recording the change of ...
Biju +33 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Development and mechanisms of photo-induced molecule junction device
NanophotonicsThe utilization of single molecule electronic devices represents a significant avenue toward advancing next-generation circuits. Recent investigations have notably augmented our understanding of the optoelectronic characteristics exhibited by diverse ...
Sun Xin +3 more
doaj +1 more source
Multiple relaxation times in single-molecule magnets
, 2016 Multiple relaxation times detected in the ac magnetic susceptibility of several single-molecule magnets have been always assigned to extrinsic factors, such as nonequivalent magnetic centers or effects of intermolecular interactions in the crystal.
Chibotaru, Liviu F., Ho, Le Tuan Anh
core +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Nanotechnology and Single Molecules
ChemPhysChem, 2004 For many years now, scientific and technological research has witnessed a dramatic increase of interest in studies of single molecules. A large number of ongoing projects are dealing with examinations of individual particles, and many of them have been funded by the Volkswagen Stiftung.
openaire +3 more sources
Single-molecule analysis of ligand efficacy in β2AR-G protein activation
Nature, 2017 G-protein-coupled receptor (GPCR)-mediated signal transduction is central to human physiology and disease intervention, yet the molecular mechanisms responsible for ligand-dependent signalling responses remain poorly understood.
G. Gregorio +13 more
semanticscholar +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source