Results 21 to 30 of about 1,163,309 (265)
Future of biomedical sciences: Single molecule microscopy [PDF]
, 2007 The behavior of single molecule defines whether a cell lives, dies, or responds to a specific drug treatment. Single molecule microscopies have begun to reveal the number, location, and functionalities of molecules outside and inside living cells.
Walter, Nils G.
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, 2022 All supplementary code for "Rapid single-molecule characterisation of DNA ...
StefanHMueller
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Verification of Single-Molecule Imaging and Single-Molecule Measurements
Journal of Robotics and Mechatronics, 2010 Single-molecule imaging and single-molecule measurements constitute an integral part of life science researches. The research method, which allows direct measurements of individual motions and events of biomolecules, has contributed much to the development of life science research by providing us with numerous findings. It is left up to the judgment of
Akihiko Ishijima +2 more
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Single‐molecule genomics [PDF]
The Journal of Pathology, 2009 AbstractThe term ‘single‐molecule genomics’ (SMG) describes a group of molecular methods in which single molecules are detected or sequenced. The focus on the analysis of individual molecules distinguishes these techniques from more traditional methods, in which template DNA is cloned or PCR‐amplified prior to analysis. Although technically challenging,
Frank, McCaughan, Paul H, Dear
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Single molecule detection for in vitro diagnostics
, 2022 Paper 68620HIn this paper we present a novel highly sensitive detection system for diagnostic applications. The system is designed to meet the needs of medical diagnostics for reliable measurements of pathogens and biomarkers in the low concentration ...
Greiner, B. +7 more
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Visualizing helicases unwinding DNA at the single molecule level. [PDF]
, 2010 DNA helicases are motor proteins that catalyze the unwinding of double-stranded DNA into single-stranded DNA using the free energy from ATP hydrolysis. Single molecule approaches enable us to address detailed mechanistic questions about how such enzymes ...
Fili, Natali +17 more
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Pulling on single molecules [PDF]
Nature Methods, 2012 Single-molecule methods to apply and measure force and displacement are expanding mechanobiology.
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A Memristive Element Based on an Electrically Controlled Single‐Molecule Reaction [PDF]
, 2020 A single-molecule memory element is electrically-controlled using two distinct reaction mechanisms as reported by K. Moth-Poulsen, J. Hihath, and co-workers (DOI:10.1002/anie.202002300).
Haipeng B. Li +14 more
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Single-Molecule Reaction-Diffusion
Biophysical Journal, 2023 Abstract We propose to capture reaction-diffusion on a molecule-by-molecule basis from the fastest acquirable timescale, namely individual photon arrivals. We illustrate our method on intrinsically disordered human proteins, the linker histone H1.0 as well as its chaperone prothymosin α
Lance W.Q. Xu +3 more
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, 2022 Paper 686204This paper presents a stochastic theory for the interpretation of photon counting histograms in fluorescence fluctuation spectroscopy (FFS). New concepts of an effective volume and a single molecule probability distribution are introduced to ...
Greiner, B., Ackermann, J., Mathis, H.
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