Results 291 to 300 of about 10,475,199 (348)
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Single-Molecule Torsional Pendulum
Science, 2005We have built a torsional pendulum based on an individual single-walled carbon nanotube, which is used as a torsional spring and mechanical support for the moving part. The moving part can be rotated by an electric field, resulting in large but fully elastic torsional deformations of the nanotube.
Meyer, J., Paillet, M., Roth, S.
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Drug Discovery Today: Technologies, 2005
Single molecule technologies provide an alternative set of approaches to conventional techniques and promise to deliver fundamentally new information about biological processes at the level of molecular movement, dynamics and function. As several of these mature and become more accessible for routine use in molecular biology laboratories, the potential
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Single molecule technologies provide an alternative set of approaches to conventional techniques and promise to deliver fundamentally new information about biological processes at the level of molecular movement, dynamics and function. As several of these mature and become more accessible for routine use in molecular biology laboratories, the potential
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Single-Molecule Optomechanical Cycle
Science, 2002Light-powered molecular machines are conjectured to be essential constituents of future nanoscale devices. As a model for such systems, we have synthesized a polymer of bistable photosensitive azobenzenes. Individual polymers were investigated by single-molecule force spectroscopy in combination with optical excitation in total internal reflection.
Hugel, T. +5 more
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2023
Fluorescence resonance energy transfer (FRET) is a photophysical phenomenon that has been repurposed as a biophysical tool to measure nanometer distances. With FRET by DNA eXchange, or FRET X, many points of interest (POIs) in a single object can be probed, overcoming a major limitation of conventional single-molecule FRET.
Filius, M. (author) +2 more
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Fluorescence resonance energy transfer (FRET) is a photophysical phenomenon that has been repurposed as a biophysical tool to measure nanometer distances. With FRET by DNA eXchange, or FRET X, many points of interest (POIs) in a single object can be probed, overcoming a major limitation of conventional single-molecule FRET.
Filius, M. (author) +2 more
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Plasmonic‐Nanopore Biosensors for Superior Single‐Molecule Detection
Advances in Materials, 2019Plasmonic and nanopore sensors have separately received much attention for achieving single‐molecule precision. A plasmonic “hotspot” confines and enhances optical excitation at the nanometer length scale sufficient to optically detect surface–analyte ...
J. Spitzberg +3 more
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2014
Single-molecule imaging is a powerful tool to understand workingmechanisms of glycoproteins and glycolipids in cell plasma membranes by overcoming intrinsically stochastic and inhomogeneous properties of biological molecular systems. Here, basic techniques for single-molecule imaging microscopy are described.
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Single-molecule imaging is a powerful tool to understand workingmechanisms of glycoproteins and glycolipids in cell plasma membranes by overcoming intrinsically stochastic and inhomogeneous properties of biological molecular systems. Here, basic techniques for single-molecule imaging microscopy are described.
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2007
The current models of eukaryotic plasma membrane organization separate the plasma membrane nto different environments created by lipids and interactions between membrane proteins and the cytoskeleton, but characterization of their physical properties, such as their sizes, lifetimes, and the partitioning of membrane components into each environment, has
Marija, Vrljic +2 more
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The current models of eukaryotic plasma membrane organization separate the plasma membrane nto different environments created by lipids and interactions between membrane proteins and the cytoskeleton, but characterization of their physical properties, such as their sizes, lifetimes, and the partitioning of membrane components into each environment, has
Marija, Vrljic +2 more
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Somatic mutation landscapes at single-molecule resolution
Nature, 2021F. Abascal +31 more
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Imaging single-molecule dichroism
Optics Letters, 1997Video-enhanced optical fluorescence microscopy has been used to determine the direction of the transition dipole moment of individual molecules. Fast electro-optical switching of the polarization of the excitation allowed us to detect the linear dichroism of single fluorophores in solid phospholipid membranes.
G J, Schtz, H, Schindler, T, Schmidt
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Oligoyne Single Molecule Wires
Journal of the American Chemical Society, 2009We report the electrical conductance at the single molecule level of the oligoyne molecular wires Py-(C[triple bond]C)(n)-Py (n = 1, 2 and 4; Py = 4-pyridyl) using STM-molecular break junction techniques in Au|molecule|Au configurations. The conductance histograms reveal multiple series of peaks attributed to differing contact geometries between the ...
Wang, Changsheng +7 more
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