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A Man for Single Molecules

ChemPhysChem, 2012
Single-molecule methods have developed into a mature and powerful research approach that is adding new insights into many different areas within the physical and life sciences. The ability to detect and perform experiments on single molecules opens up new experimental approaches to investigating the physical world.
Thomas, Bein   +2 more
openaire   +2 more sources

Force applied to a single molecule at a single nanogate molecule filter

Nanoscale, 2010
We have investigated the origin of molecule filtering system based on a chemical potential barrier produced by thermodynamically driven molecular flow in a nanoscopic space at nanogates. Single molecule tracking experiments prove that the highly localized potential barrier allows for selective manipulation of the target molecule.
Baku, Takimoto   +2 more
openaire   +2 more sources

Single-Molecule Tracking

2007
The current models of eukaryotic plasma membrane organization separate the plasma membrane nto different environments created by lipids and interactions between membrane proteins and the cytoskeleton, but characterization of their physical properties, such as their sizes, lifetimes, and the partitioning of membrane components into each environment, has
Marija, Vrljic   +2 more
openaire   +2 more sources

Single-Molecule Torsional Pendulum

Science, 2005
We have built a torsional pendulum based on an individual single-walled carbon nanotube, which is used as a torsional spring and mechanical support for the moving part. The moving part can be rotated by an electric field, resulting in large but fully elastic torsional deformations of the nanotube.
Meyer, J., Paillet, M., Roth, S.
openaire   +3 more sources

Single molecule technologies

Drug Discovery Today: Technologies, 2005
Single molecule technologies provide an alternative set of approaches to conventional techniques and promise to deliver fundamentally new information about biological processes at the level of molecular movement, dynamics and function. As several of these mature and become more accessible for routine use in molecular biology laboratories, the potential
openaire   +2 more sources

Single Molecule Imaging

2014
Single-molecule imaging is a powerful tool to understand workingmechanisms of glycoproteins and glycolipids in cell plasma membranes by overcoming intrinsically stochastic and inhomogeneous properties of biological molecular systems. Here, basic techniques for single-molecule imaging microscopy are described.
openaire   +1 more source

Single molecule nano-bioscience

TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664), 2004
Summary form only given. Biomolecules assemble to form molecular machines such as molecular motors, cell signal processors, DNA transcription processors and protein synthesizers to fulfill their functions. Their collaboration allows the activity of biological systems.
openaire   +1 more source

Single‐Molecule Dynamic Triangulation

ChemPhysChem, 2006
AbstractA proposal for using single molecules as nanoprobes capable of detecting the trajectory of an elementary charge is discussed in detail. Presented numerical simulations prove that this single‐molecule technique allows determination of a three‐dimensional single‐electron displacement within a few seconds with an accuracy better than 0.006 nm ...
openaire   +5 more sources

Modulating single-molecule charge transport through external stimulus

EScience, 2023
Yaping Zang, Latha Venkataraman, Qi Zou
exaly  

Optical tweezers in single-molecule biophysics

Nature Reviews Methods Primers, 2021
Michelle D. Wang   +2 more
exaly  

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