Results 281 to 290 of about 1,178,188 (315)
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Single-Molecule Mechanoenzymatics
Annual Review of Biophysics, 2012The ability of cellular signaling networks to sense, process, and respond to internal and external stimuli relies on their specific detection and transduction based on molecular recognition. The molecular mechanisms by which force is specifically sensed by mechanoenzymatic processes, translated into biochemical signals, and wired to cellular signaling
Elias M, Puchner, Hermann E, Gaub
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Annual Review of Physical Chemistry, 2004
▪ Abstract  We review recent developments in single-molecule spectroscopy and microscopy. New optical methods provide access to the absorption, emission, or excitation spectra of single nano-objects and can determine either the positions of these objects with subwavelength accuracy or the full three-dimensional orientation of their transition dipole ...
Florian, Kulzer, Michel, Orrit
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▪ Abstract  We review recent developments in single-molecule spectroscopy and microscopy. New optical methods provide access to the absorption, emission, or excitation spectra of single nano-objects and can determine either the positions of these objects with subwavelength accuracy or the full three-dimensional orientation of their transition dipole ...
Florian, Kulzer, Michel, Orrit
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2007
The current models of eukaryotic plasma membrane organization separate the plasma membrane nto different environments created by lipids and interactions between membrane proteins and the cytoskeleton, but characterization of their physical properties, such as their sizes, lifetimes, and the partitioning of membrane components into each environment, has
Marija, Vrljic +2 more
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The current models of eukaryotic plasma membrane organization separate the plasma membrane nto different environments created by lipids and interactions between membrane proteins and the cytoskeleton, but characterization of their physical properties, such as their sizes, lifetimes, and the partitioning of membrane components into each environment, has
Marija, Vrljic +2 more
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Force applied to a single molecule at a single nanogate molecule filter
Nanoscale, 2010We have investigated the origin of molecule filtering system based on a chemical potential barrier produced by thermodynamically driven molecular flow in a nanoscopic space at nanogates. Single molecule tracking experiments prove that the highly localized potential barrier allows for selective manipulation of the target molecule.
Baku, Takimoto +2 more
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Single-Molecule Torsional Pendulum
Science, 2005We have built a torsional pendulum based on an individual single-walled carbon nanotube, which is used as a torsional spring and mechanical support for the moving part. The moving part can be rotated by an electric field, resulting in large but fully elastic torsional deformations of the nanotube.
Meyer, J., Paillet, M., Roth, S.
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Drug Discovery Today: Technologies, 2005
Single molecule technologies provide an alternative set of approaches to conventional techniques and promise to deliver fundamentally new information about biological processes at the level of molecular movement, dynamics and function. As several of these mature and become more accessible for routine use in molecular biology laboratories, the potential
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Single molecule technologies provide an alternative set of approaches to conventional techniques and promise to deliver fundamentally new information about biological processes at the level of molecular movement, dynamics and function. As several of these mature and become more accessible for routine use in molecular biology laboratories, the potential
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2014
Single-molecule imaging is a powerful tool to understand workingmechanisms of glycoproteins and glycolipids in cell plasma membranes by overcoming intrinsically stochastic and inhomogeneous properties of biological molecular systems. Here, basic techniques for single-molecule imaging microscopy are described.
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Single-molecule imaging is a powerful tool to understand workingmechanisms of glycoproteins and glycolipids in cell plasma membranes by overcoming intrinsically stochastic and inhomogeneous properties of biological molecular systems. Here, basic techniques for single-molecule imaging microscopy are described.
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Single-Molecule Optomechanical Cycle
Science, 2002Light-powered molecular machines are conjectured to be essential constituents of future nanoscale devices. As a model for such systems, we have synthesized a polymer of bistable photosensitive azobenzenes. Individual polymers were investigated by single-molecule force spectroscopy in combination with optical excitation in total internal reflection.
Hugel, T. +5 more
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Single-Molecule Analysis of Chromatin
2003Publisher Summary This chapter describes the technical details of three single-molecule techniques that are utilized for the study of single chromatin fibers including the atomic force microscope (AFM), optical tweezers (OT), and magnetic tweezers (MT).
Leuba, S.H. +2 more
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Single molecule nano-bioscience
TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664), 2004Summary form only given. Biomolecules assemble to form molecular machines such as molecular motors, cell signal processors, DNA transcription processors and protein synthesizers to fulfill their functions. Their collaboration allows the activity of biological systems.
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