Results 81 to 90 of about 10,451,032 (401)

Topoisomerase VI is a chirally-selective, preferential DNA decatenase

eLife, 2022
DNA topoisomerase VI (topo VI) is a type IIB DNA topoisomerase found predominantly in archaea and some bacteria, but also in plants and algae. Since its discovery, topo VI has been proposed to be a DNA decatenase; however, robust evidence and a mechanism
Shannon J McKie, Parth Rakesh Desai, Yeonee Seol, Adam MB Allen, Anthony Maxwell, Keir C Neuman   +5 more
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Nature Communications
Widespread manganese-sensing transcriptional riboswitches effect the dependable gene regulation needed for bacterial manganese homeostasis in changing environments.
Adrien Chauvier, Shiba S. Dandpat, Rosa Romero, Nils G. Walter   +3 more
doaj   +1 more source

Overview of Single-Molecule Speckle (SiMS) Microscopy and Its Electroporation-Based Version with Efficient Labeling and Improved Spatiotemporal Resolution

Sensors, 2017
Live-cell single-molecule imaging was introduced more than a decade ago, and has provided critical information on remodeling of the actin cytoskeleton, the motion of plasma membrane proteins, and dynamics of molecular motor proteins. Actin remodeling has
Sawako Yamashiro, Naoki Watanabe
doaj   +1 more source

Single-molecule nanopore enzymology [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2017
Biological nanopores are a class of membrane proteins that open nanoscale water conduits in biological membranes. When they are reconstituted in artificial membranes and a bias voltage is applied across the membrane, the ionic current passing through individual nanopores can be used to monitor chemical reactions, to recognize individual molecules and ...
Kherim Willems, Veerle Van Meervelt, Carsten Wloka, Giovanni Maglia   +3 more
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Viruses and Tetraspanins: Lessons from Single Molecule Approaches

Viruses, 2014
Tetraspanins are four-span membrane proteins that are widely distributed in multi-cellular organisms and involved in several infectious diseases. They have the unique property to form a network of protein-protein interaction within the plasma membrane ...
Selma Dahmane, Eric Rubinstein, Pierre-Emmanuel Milhiet   +2 more
doaj   +1 more source

Single molecule transcription elongation [PDF]

Methods, 2009
Single molecule optical trapping assays have now been applied to a great number of macromolecular systems including DNA, RNA, cargo motors, restriction enzymes, DNA helicases, chromosome remodelers, DNA polymerases and both viral and bacterial RNA polymerases.
Galburt, E., Grill, S., Bustamante, C.
openaire   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Single-molecule Electronics: Cooling Individual Vibrational Modes by the Tunneling Current

, 2015
Electronic devices composed of single molecules constitute the ultimate limit in the continued downscaling of electronic components. A key challenge for single-molecule electronics is to control the temperature of these junctions. Controlling heating and
Gagliardi, Alessio, Lykkebo, Jacob, Pecchia, Alessandro, Romano, Giuseppe, Solomon, Gemma C.   +4 more
core   +1 more source