Results 31 to 40 of about 310,423 (261)
Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis
Internalized receptors are recycled back to the cell surface, but their precise mechanisms are unclear. Here, the authors show that the flotillin membrane proteins may regulate the transfer of internalized T cell receptors into Rab5 and Rab11-positive ...
Gregory M. I. Redpath +8 more
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Imaging of single molecules [PDF]
n ...
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Depression and anxiety are common, debilitating psychiatric conditions affecting millions of people throughout the world. Current treatments revolve around selective serotonin reuptake inhibitors (SSRIs), yet these drugs are only moderately effective at ...
Nikita Deo, Gregory Redpath
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Tethered Signaling in Inhibitory Immune Receptors
Leukocytes play critical roles in preventing pathogenic infection and controlling transformed cells, but must remain quiescent in response to healthy tissue.
Pablo Pérez-Ferreros +5 more
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Single-Molecule Imaging of Nuclear Transport [PDF]
The utility of single molecule fluorescence microscopy approaches has been proven to be of a great avail in understanding biological reactions over the last decade. The investigation of molecular interactions with high temporal and spatial resolutions deep within cells has remained challenging due to the inherently weak signals arising from individual ...
Alexander, Goryaynov +3 more
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Introducing Membrane Charge and Membrane Potential to T Cell Signaling
While membrane models now include the heterogeneous distribution of lipids, the impact of membrane charges on regulating the association of proteins with the plasma membrane is often overlooked.
Yuanqing Ma +7 more
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An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging.
Yuanqing Ma +8 more
doaj +1 more source
Graphene: Preparation, tailoring, and modification
Graphene is a 2D material with fruitful electrical properties, which can be efficiently prepared, tailored, and modified for a variety of applications, particularly in the field of optoelectronic devices thanks to its planar hexagonal lattice structure ...
Mingyao Li +6 more
doaj +1 more source
Novel Fluorophores for Single-Molecule Imaging [PDF]
Nonlinear optical chromophores based on dicyanodihydrofuran acceptors paired with amine donors have been found to exhibit sufficiently large fluorescence quantum yields and stability to enable single-molecule detection in polymeric hosts. To illustrate the breadth of this class, six fluorophores are presented, spanning the emission range from 505 to ...
Katherine A, Willets +4 more
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Single-molecule recognition imaging microscopy [PDF]
Atomic force microscopy is a powerful and widely used imaging technique that can visualize single molecules and follow processes at the single-molecule level both in air and in solution. For maximum usefulness in biological applications, atomic force microscopy needs to be able to identify specific types of molecules in an image, much as fluorescent ...
C, Stroh +8 more
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