Results 31 to 40 of about 310,423 (261)

Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis

open access: yesNature Communications, 2019
Internalized receptors are recycled back to the cell surface, but their precise mechanisms are unclear. Here, the authors show that the flotillin membrane proteins may regulate the transfer of internalized T cell receptors into Rab5 and Rab11-positive ...
Gregory M. I. Redpath   +8 more
doaj   +1 more source

Imaging of single molecules [PDF]

open access: yesActa Crystallographica Section A Foundations of Crystallography, 2005
n ...
openaire   +1 more source

Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety

open access: yesFrontiers in Cellular Neuroscience, 2022
Depression and anxiety are common, debilitating psychiatric conditions affecting millions of people throughout the world. Current treatments revolve around selective serotonin reuptake inhibitors (SSRIs), yet these drugs are only moderately effective at ...
Nikita Deo, Gregory Redpath
doaj   +1 more source

Tethered Signaling in Inhibitory Immune Receptors

open access: yesFrontiers in Physics, 2019
Leukocytes play critical roles in preventing pathogenic infection and controlling transformed cells, but must remain quiescent in response to healthy tissue.
Pablo Pérez-Ferreros   +5 more
doaj   +1 more source

Single-Molecule Imaging of Nuclear Transport [PDF]

open access: yesJournal of Visualized Experiments, 2010
The utility of single molecule fluorescence microscopy approaches has been proven to be of a great avail in understanding biological reactions over the last decade. The investigation of molecular interactions with high temporal and spatial resolutions deep within cells has remained challenging due to the inherently weak signals arising from individual ...
Alexander, Goryaynov   +3 more
openaire   +2 more sources

Introducing Membrane Charge and Membrane Potential to T Cell Signaling

open access: yesFrontiers in Immunology, 2017
While membrane models now include the heterogeneous distribution of lipids, the impact of membrane charges on regulating the association of proteins with the plasma membrane is often overlooked.
Yuanqing Ma   +7 more
doaj   +1 more source

An intermolecular FRET sensor detects the dynamics of T cell receptor clustering

open access: yesNature Communications, 2017
Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging.
Yuanqing Ma   +8 more
doaj   +1 more source

Graphene: Preparation, tailoring, and modification

open access: yesExploration, 2023
Graphene is a 2D material with fruitful electrical properties, which can be efficiently prepared, tailored, and modified for a variety of applications, particularly in the field of optoelectronic devices thanks to its planar hexagonal lattice structure ...
Mingyao Li   +6 more
doaj   +1 more source

Novel Fluorophores for Single-Molecule Imaging [PDF]

open access: yesJournal of the American Chemical Society, 2003
Nonlinear optical chromophores based on dicyanodihydrofuran acceptors paired with amine donors have been found to exhibit sufficiently large fluorescence quantum yields and stability to enable single-molecule detection in polymeric hosts. To illustrate the breadth of this class, six fluorophores are presented, spanning the emission range from 505 to ...
Katherine A, Willets   +4 more
openaire   +2 more sources

Single-molecule recognition imaging microscopy [PDF]

open access: yesProceedings of the National Academy of Sciences, 2004
Atomic force microscopy is a powerful and widely used imaging technique that can visualize single molecules and follow processes at the single-molecule level both in air and in solution. For maximum usefulness in biological applications, atomic force microscopy needs to be able to identify specific types of molecules in an image, much as fluorescent ...
C, Stroh   +8 more
openaire   +2 more sources

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