Results 11 to 20 of about 7,224,188 (257)
Single-molecule imaging technologies, especially those based on fluorescence, have been developed to probe both the equilibrium and dynamic properties of biomolecules at the single-molecular and quantitative levels. In this review, we provide an overview
Louis Colson +6 more
doaj +2 more sources
Single-molecule nano-optics at low temperature [PDF]
The work presented in this thesis involves experiments on single molecules at low temperature. At low temperature, many disturbing temperature activated processes are frozen out, resulting in extremely sharp zero-phonon lines in the fluorescence ex ...
Butter, Jacqueline Yvonne Paula
core +1 more source
songuno1/single-molecule-assay: Single-molecule assay analysis
Single-molecule assay analysis tool for "Transcriptional pause extension benefits the stand-by rather than catch-up Rho-dependent termination"
Eunho Song
core +1 more source
SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling
T cell activation requires engagement of a cognate antigen by the T cell receptor (TCR) and the co-stimulatory signal of CD28. Both TCR and CD28 aggregate into clusters at the plasma membrane of activated T cells.
Manuela Ecker +9 more
doaj +1 more source
Real-Time analysis and visualization for single-molecule based super-resolution microscopy [PDF]
Accurate multidimensional localization of isolated fluorescent emitters is a time consuming process in single-molecule based super-resolution microscopy.
Jean-Baptiste Sibarita +9 more
core +1 more source
Single molecule detection for in vitro diagnostics
Paper 68620HIn this paper we present a novel highly sensitive detection system for diagnostic applications. The system is designed to meet the needs of medical diagnostics for reliable measurements of pathogens and biomarkers in the low concentration ...
Greiner, B. +7 more
core +1 more source
T Cell Membrane Heterogeneity Aids Antigen Recognition and T Cell Activation
T cells are critical for co-ordinating the immune response. T cells are activated when their surface T cell receptors (TCRs) engage cognate antigens in the form of peptide-major histocompatibility complexes (pMHC) presented on the surface of antigen ...
Megan V. Farrell +7 more
doaj +1 more source
Building a Total Internal Reflection Microscope (TIRF) with Active Stabilization (Feedback SMLM)
The data quality of high-resolution imaging can be markedly improved with active stabilization, which is based on feedback loops within the microscope that maintain the sample in the same location throughout the experiment.
Simao Coelho +3 more
doaj +1 more source
Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro
The stability of the HIV-1 capsid and the spatiotemporal control of its disassembly, a process called uncoating, need to be finely tuned for infection to proceed.
Chantal Márquez +6 more
doaj +1 more source
York et al employ lattice light-sheet microscopy to study the initial events following activation of the epidermal growth factor receptor (EGFR) in whole live cells.
H. M. York +9 more
doaj +1 more source

