Results 171 to 180 of about 1,653,696 (343)

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

Advanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby, Yulia Marom, Guocong Lin, Aleksandra Baron‐Wiechec, Amit Meller   +4 more
wiley   +1 more source

Somatic mutation finder (SMUFIN) to identify single-nucleotide variants (SNVs) and structural variants in tumor DNA [PDF]

, 2014

openalex   +1 more source

Predicting the functional impact of single nucleotide variants in Drosophila melanogaster with FlyCADD. [PDF]

Genetics
Beets J, Höglund J, Kim BY, Ellers J, Hoedjes KM, Bosse M.   +5 more
europepmc   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Validation of Chromosomal Locations of 90K Array Single Nucleotide Polymorphisms in US Wheat [PDF]

, 2015
Shuyu Liu, Silvano O. Assanga, Smit Dhakal, Xiangkun Gu, Chor‐Tee Tan, Yan Yang, Jackie C. Rudd, Dirk B. Hays, Amir M. H. Ibrahim, Qingwu Xue, Shiaoman Chao, Ravindra N. Devkota, Cody Shachter, Trevis D. Huggins, Suheb Mohammed, Maria P. Fuentealba   +15 more
openalex   +1 more source

gutMSNP: a comprehensive database for human gut microbial single-nucleotide polymorphisms. [PDF]

Nucleic Acids Res
Qian K, Du M, Tan S, Ding M, Song M, Lu M, Qi C, Cheng L, Zhang X.   +8 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Annotating the genome at single-nucleotide resolution with DNA foundation models. [PDF]

Nat Methods
de Almeida BP, Dalla-Torre H, Richard G, Blum C, Hexemer L, Gélard M, Mendoza-Revilla J, Tang Z, Marin FI, Emms DM, Pandey P, Laurent S, Lopez M, Laterre A, Lang M, Şahin U, Beguir K, Pierrot T.   +17 more
europepmc   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source