Results 171 to 180 of about 1,522,500 (352)

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

, 1999
Christian L. Lorson, Eric Hahnen, Elliot J. Androphy, Brunhilde Wirth   +3 more
openalex   +1 more source

SNPing Away at Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease [PDF]

, 2000
Eden R. Martin, Eric Lai, John R. Gilbert, Allison R. Rogala, Afsoon Afshari, John Riley, Kelly Finch, Jeffery Stevens, Ken Livak, Brandon D. Slotterbeck, Susan H. Slifer, Liling Warren, P. Michael Conneally, Donald E. Schmechel, Ian J. Purvis, Margaret A. Pericak‐Vance, Allen D. Roses, Jeffery M. Vance   +17 more
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

CYP19A1 single nucleotide polymorphism associations with CYP19A1, NFκB1, and IL6 gene expression in human normal colon and normal liver samples

Pharmacogenomics and Personalized Medicine, 2014
Rosalind B Penney,1 Abbie Lundgreen,2 Aiwei Yao-Borengasser,3 Vineetha K Edavana,3 Suzanne Williams,3 Ishwori Dhakal,4 Roger K Wolff,2 Susan Kadlubar,3 Martha L Slattery2 1Department of Environmental and Occupational Health, University of Arkansas for ...
Penney RB, Lundgreen A, Yao-Borengasser A, Edavana VK, Williams S, Dhakal I, Wolff RK, Kadlubar S, Slattery ML   +8 more
doaj  

Single-nucleotide polymorphisms and other mismatches reduce performance of quantitative PCR assays [PDF]

, 2013
HELLEMANS, JAN, Lefever, Steve, Pattyn, Filip, Vandesompele, Jo   +3 more
core   +2 more sources

Single nucleotide polymorphism and linkage disequilibrium within the TCR alpha/delta locus [PDF]

, 2000
Miriam F. Moffatt
openalex   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer

Lung Cancer: Targets and Therapy, 2011
Shanbeh Zienolddiny, Vidar SkaugSection for Toxicology and Biological Work Environment, National Institute of Occupational Health, Oslo, NorwayAbstract: Lung cancer is a major public health problem throughout the world.
Zienolddiny S, Skaug V
doaj  

Comparison of three methods for single nucleotide polymorphism typing for DNA bank studies: Sequence-specific oligonucleotide probe hybridisation, TaqMan liquid phase hybridisation, and microplate array diagonal gel electrophoresis (MADGE)

, 1999
John W. Holloway, Bianca Begh�, Steve Turner, Lesley J. Hinks, Ian N. M. Day, W. M. Howell   +5 more
openalex   +1 more source

A Microsphere-Based Assay for Multiplexed Single Nucleotide Polymorphism Analysis Using Single Base Chain Extension [PDF]

, 2000
Jingwen Chen, Marie A. Iannone, May-Sung Li, J. David Taylor, Philip Rivers, Anita J. Nelsen, Kimberly Slentz‐Kesler, Allen D. Roses, Michael P. Weiner   +8 more
openalex   +1 more source