Results 221 to 230 of about 1,522,500 (352)

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

Advanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee, Ali Kiapour, Brendan D. Stoeckl, Ellen Y. Zhang, Matthew R. Begley, Jarod Oldham, Lewis Harrison, Jessee Hunt, Robert L. Mauck, Su Chin Heo   +9 more
wiley   +1 more source

Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene [PDF]

, 2000
Toyokazu Seki, Toshihiro Tanaka, Yusuke Nakamura   +2 more
openalex   +1 more source

Association analysis of single nucleotide polymorphisms in the LIFR gene with lambing number in sheep. [PDF]

Front Vet Sci
Wen Y, Xiang Y, Zhang R, Liu K, Liu Y, Chu M.   +5 more
europepmc   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability [PDF]

, 2000
Hideo Orimo, Eiitsu Nakajima, M. Yamamoto, Miyoko Ikejima, M. Emi, Takashi Shimada   +5 more
openalex   +1 more source

PRP: pathogenic risk prediction for rare nonsynonymous single nucleotide variants. [PDF]

Hum Genet
Heo JY, Kim JH.
europepmc   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Parallel Genotyping of 10,204 Single Nucleotide Polymorphisms to Screen for Susceptible Genes for IgA Nephropathy

, 2000
Keng Thye Woo, Yeow Kok Lau, Kok‐Seng Wong, Yi Zhao, Choong Meng Chan   +4 more
openalex   +1 more source

Estimation of Population Parameters and Recombination Rates From Single Nucleotide Polymorphisms [PDF]

, 2000
Rasmus Nielsen
openalex   +1 more source

DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. [PDF]

Genome Biol
Kang S, Borgsmüller N, Valecha M, Markowska M, Kuipers J, Beerenwinkel N, Posada D, Szczurek E.   +7 more
europepmc   +1 more source