Results 21 to 30 of about 1,522,500 (352)

Assessment of possible association between rs378854 and prostate cancer risk in the Serbian population [PDF]

Archives of Biological Sciences, 2013
Prostate cancer (PCa) is the second most commonly diagnosed cancer among men worldwide. Despite its high incidence rate, the molecular basis of PCa onset and its progression remains little understood.
Brajušković G., Nikolić Zorana, Kojić A., Savić-Pavićević Dušanka, Cerović Snežana, Tomović S., Filipović Nataša, Vukotić Vinka, Romac Stanka   +8 more
doaj   +1 more source

Investigations into the molecular effects of single nucleotide polymorphism [PDF]

, 2000
Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe
core   +1 more source

Association of Single Nucleotide Polymorphisms in Nucleotide-Binding Domain Leucine-Rich Repeat Protein 1 with Clostridioides difficile Colonization or Infection

Infection and Drug Resistance, 2023
Bo-Yang Tsai,1,* Pei-Jane Tsai,1– 4,* Ching-Chi Lee,5,6 Chun-Wei Chiu,7 Yi-Hsin Lai,4 Jen-Chieh Lee,6 Wen-Chien Ko,6,8 Yuan-Pin Hung6– 9 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan ...
Tsai BY, Tsai PJ, Lee CC, Chiu CW, Lai YH, Lee JC, Ko WC, Hung YP   +7 more
doaj  

Periodic correlation structures in bacterial and archaeal complete genomes [PDF]

, 2013
The periodic transference of nucleotide strings in bacterial and archaeal complete genomes is investigated by using the metric representation and the recurrence plot method.
Wu, Zuo-Bing
core   +1 more source

Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies

Cells, 2019
Mitochondrial genome-wide association studies identify mitochondrial single nucleotide polymorphisms (mtSNPs) that associate with disease or disease-related phenotypes.
Brendan Miller, Thalida E. Arpawong, Henry Jiao, Su-Jeong Kim, Kelvin Yen, Hemal H. Mehta, Junxiang Wan, John C. Carpten, Pinchas Cohen   +8 more
doaj   +1 more source

Association of the rs8720 and rs12587 KRAS Gene Variants with Colorectal Cancer in a Mexican Population and Their Analysis In Silico

Cells, 2023
Colorectal cancer (CRC) is a major global health challenge and one of the top 10 cancers in Mexico. Lifestyle and genetic factors influence CRC development, prognosis, and therapeutic response; identifying risk factors, such as the genes involved, is ...
Martha Patricia Gallegos-Arreola, Asbiel Felipe Garibaldi-Ríos, José Israel Cruz-Sánchez, Luis Eduardo Figuera, Carlos Alberto Ronquillo-Carreón, Mónica Alejandra Rosales-Reynoso, Belinda Claudia Gómez-Meda, Irving Alejandro Carrillo-Dávila, Ana María Puebla-Pérez, Héctor Montoya-Fuentes, Valeria Peralta-Leal, Guillermo M. Zúñiga-González   +11 more
doaj   +1 more source

p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]

, 2016
BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G, Fan, LM, Ghazaly, MM, Howlin, B, Krönke, M, Li, J-M, Meijles, DN   +6 more
core   +1 more source

Inferring clonal evolution of tumors from single nucleotide somatic mutations [PDF]

, 2013
High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations.
Deshwar, Amit G., Jiao, Wei, Morris, Quaid, Stein, Lincoln, Vembu, Shankar   +4 more
core   +2 more sources

Kinesin's backsteps under mechanical load [PDF]

, 2009
Kinesins move processively toward the plus end of microtubules by hydrolyzing ATP for each step. From an enzymatic perspective, the mechanism of mechanical motion coupled to the nucleotide chemistry is often well explained using a single-loop cyclic ...
Alberty, Alonso, Asbury, Baker, Beeg, Bell, Block, Block, Block, Brady, Brant, Carter, Changbong Hyeon, Chemla, Coppin, Coppin, Cross, Cross, Fisher, Fisher, Gelles, Gilbert, Gross, Guydosh, Hackney, Hackney, Howard, Hunt, Hyeon, Hyeon, Itoh, José N. Onuchic, Kawaguchi, Klumpp, Kojima, Kolomeisky, Liepelt, Liphardt, Lipowsky, Ma, Meyhofer, Mickler, Mori, Moyer, Muller, Nishiyama, Nishiyama, Oster, Qian, Qu, Reimann, Rice, Rice, Ross, Russell, Schief, Schief, Schnitzer, Schnitzer, Stefan Klumpp, Svoboda, Taniguchi, Thirumalai, Tsygankov, Uemura, Uemura, Vale, Vale, Visscher, Wu, Yildiz, Yildiz   +71 more
core   +1 more source

The Association Between AURKA Gene rs2273535 Polymorphism and Gastric Cancer Risk in a Chinese Population

Frontiers in Physiology, 2018
The Aurora kinase A (AURKA) gene is frequently amplified and overexpressed in gastric cancer (GC). The overexpression of AURKA promotes inflammation and tumorigenesis in GC.
Xiaoyan Zhou, Pengli Wang, Hui Zhao
doaj   +1 more source